The cell nucleus is a highly crowded environment, filled with a multicomponent,
polydisperse mixture of biopolymers and nuclear bodies dispersed in a viscous solvent. With …

Successful prediction of protein folding from an amino acid sequence is a challenge in
computational biology. In order to reveal the geometric constraints that drive protein folding …

A flexible polymer chain in the presence of inert macromolecular crowders will experience a
loss of configurational entropy due to the crowder excluded volume. This entropy reduction …

Wang–Landau sampling is implemented on the Graphics Processing Unit (GPU) with the
Compute Unified Device Architecture (CUDA). Performances on three different GPU cards …

Depletion-induced interactions between colloids in colloid–polymer mixtures depend in
range and strength on size, shape, and concentration of depletants. Crowding by colloids in …

As first explained by the classic Asakura–Oosawa (AO) model, effective attractive forces
between colloidal particles induced by depletion of nonadsorbing polymers can drive …

Depletion forces and macromolecular crowding govern the structure and function of
biopolymers in biological cells and the properties of polymer nanocomposite materials. To …

Effective coarse-grained representations of protein-protein interaction potentials are vital in
the modeling of large scale systems. We develop a method to fit an arbitrary number of …

In this review, we begin by describing the importance of studying the processes of protein
self-assembly for understanding the formation of natural protein polymers, disease-causing …

Many biological systems are containing high contents of various macromolecular and
colloidal species, they may thus be considered as an aqueous suspension with a high …