Nanopore sensing is an attractive, label‐free approach that can measure single molecules.
Although initially proposed for rapid and low‐cost DNA sequencing, nanopore sensors have …

Aggregates of misfolded proteins are associated with several devastating
neurodegenerative diseases. These so‐called amyloids are therefore explored as …

This paper demonstrates that high-bandwidth current recordings in combination with low-
noise silicon nitride nanopores make it possible to determine the molecular volume …

The ability to detect and distinguish biomolecules at the single‐molecule level is at the
forefront of today's biomedicine and analytical chemistry research. Increasing the dwell time …

DNA in cells is heavily covered with all types of proteins that regulate its genetic activity.
Detection of DNA-bound proteins is a challenge that is well suited to solid-state nanopores …

Enzymes and motor proteins are dynamic macromolecules that coexist in a number of
conformations of similar energies. Protein function is usually accompanied by a change in …

DNA is the primary target of many anticancer drugs involved in important intercellular
processes, especially in transcriptional regulation, and histone is known to inhibit gene …

While understanding translocation of DNA through a solid-state nanopore is vital for
exploiting its potential for sensing and sequencing at the single-molecule level, surprisingly …

In this article, we introduce a flexible technique for high-throughput solid-state nanopore
analysis of single biomolecules. By confining the electrolyte to a micron-scale liquid …

In the 1940s Wallace Coulter set about finding a way to quickly count blood cells, which at
the time was a slow and inefficient process. His approach was to pass cells, one by one …