Neurorestorative therapy for stroke
J Chen, P Venkat, A Zacharek… - Frontiers in human …, 2014 - frontiersin.org
Ischemic stroke is responsible for many deaths and long-term disability world wide.
Development of effective therapy has been the target of intense research. Accumulating …
Development of effective therapy has been the target of intense research. Accumulating …
[HTML][HTML] The role of microRNAs in self-renewal and differentiation of mesenchymal stem cells
L Guo, RCH Zhao, Y Wu - Experimental hematology, 2011 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs involved in post-trascriptional regulation
of gene expression and diverse biological activities. They are crucial for self-renewal and …
of gene expression and diverse biological activities. They are crucial for self-renewal and …
Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
Extracellular vesicles (EVs) secreted by cells present an attractive strategy for developing
new therapies, but progress in the field is limited by several issues: The quality of the EVs …
new therapies, but progress in the field is limited by several issues: The quality of the EVs …
Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth
H Xin, Y Li, B Buller, M Katakowski, Y Zhang… - Stem …, 2012 - academic.oup.com
Multipotent mesenchymal stromal cells (MSCs) have potential therapeutic benefit for the
treatment of neurological diseases and injury. MSCs interact with and alter brain …
treatment of neurological diseases and injury. MSCs interact with and alter brain …
Exosomes derived from bone marrow mesenchymal stem cells promote angiogenesis in ischemic stroke mice via upregulation of MiR-21-5p
H Hu, X Hu, L Li, Y Fang, Y Yang, J Gu, J Xu, L Chu - Biomolecules, 2022 - mdpi.com
Exosomes derived from bone mesenchymal stem cells (BMSC-Exos) are one of the main
factors responsible for the therapeutic effects of BMSCs. The study aimed to investigate …
factors responsible for the therapeutic effects of BMSCs. The study aimed to investigate …
Mesenchymal stem cells as a multimodal treatment for nervous system diseases
B Badyra, M Sułkowski, O Milczarek… - Stem Cells …, 2020 - academic.oup.com
Neurological disorders are a massive challenge for modern medicine. Apart from the fact
that this group of diseases is the second leading cause of death worldwide, the majority of …
that this group of diseases is the second leading cause of death worldwide, the majority of …
Therapeutic advancement in neuronal transdifferentiation of mesenchymal stromal cells for neurological disorders
Neurodegenerative disorders have become the leading cause of chronic pain and death.
Treatments available are not sufficient to help the patients as they only alleviate the …
Treatments available are not sufficient to help the patients as they only alleviate the …
Exploring the cell signalling in hepatocyte differentiation
R Vasconcellos, ÉC Alvarenga, RC Parreira, SS Lima… - Cellular signalling, 2016 - Elsevier
The liver is the second largest organ in the human body and is responsible for several
functions that directly contribute to homeostasis. Hepatocytes are the main parenchymal …
functions that directly contribute to homeostasis. Hepatocytes are the main parenchymal …
MicroRNAs and their potential therapeutic applications in neural tissue engineering
The inherent poor regeneration capacity of nerve tissues, especially in the central nervous
system, poses a grand challenge for neural tissue engineering. After injuries, the local …
system, poses a grand challenge for neural tissue engineering. After injuries, the local …
MicroRNA expression patterns in human anterior cingulate and motor cortex: A study of dementia with Lewy bodies cases and controls
Overview MicroRNAs (miRNAs) have been implicated in neurodegenerative diseases
including Parkinson's disease and Alzheimer's disease (AD). Here, we evaluated the …
including Parkinson's disease and Alzheimer's disease (AD). Here, we evaluated the …