[HTML][HTML] The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
The synthesis and functionalization of iron oxide nanoparticles (IONPs) is versatile, which
has enhanced the interest in studying them as theranostic agents over recent years. As …

[HTML][HTML] Tumor immune microenvironment and immunotherapy in brain metastasis from non-small cell lung cancer

Y Wang, R Chen, Y Wa, S Ding, Y Yang, J Liao… - Frontiers in …, 2022 - frontiersin.org
Brain metastasis (BM), a devastating complication of advanced malignancy, has a high
incidence in non-small cell lung cancer (NSCLC). As novel systemic treatment drugs and …

[HTML][HTML] Classification of tumor immune microenvironment according to programmed death-ligand 1 expression and immune infiltration predicts response to …

D Sun, J Liu, H Zhou, M Shi, J Sun, S Zhao… - Journal of Thoracic …, 2023 - Elsevier
Introduction According to mechanisms of adaptive immune resistance, tumor immune
microenvironment (TIME) is classified into four types:(1) programmed death-ligand 1 (PD …

[HTML][HTML] Neuroinflammatory gene expression analysis reveals pathways of interest as potential targets to improve the recording performance of intracortical …

S Song, B Regan, ES Ereifej, ER Chan, JR Capadona - Cells, 2022 - mdpi.com
Intracortical microelectrodes are a critical component of brain-machine interface (BMI)
systems. The recording performance of intracortical microelectrodes used for both basic …

[HTML][HTML] Radiomics for the non-invasive prediction of PD-L1 expression in patients with brain metastases secondary to non-small cell lung cancer

AK Meißner, R Gutsche, N Galldiks, M Kocher… - Journal of neuro …, 2023 - Springer
Background The expression level of the programmed cell death ligand 1 (PD-L1) appears to
be a predictor for response to immunotherapy using checkpoint inhibitors in patients with …

[HTML][HTML] Harnessing immunotherapy for brain metastases: insights into tumor–brain microenvironment interactions and emerging treatment modalities

D Zhou, Z Gong, D Wu, C Ma, L Hou, X Niu… - Journal of Hematology & …, 2023 - Springer
Brain metastases signify a deleterious milestone in the progression of several advanced
cancers, predominantly originating from lung, breast and melanoma malignancies, with a …

[HTML][HTML] FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response

O Bogatyrova, JSM Mattsson, EM Ross… - European Journal of …, 2021 - Elsevier
Amplification of fibroblast growth factor receptor 1 (FGFR1) in non-small cell lung cancer
(NSCLC) has been considered as an actionable drug target. However, pan-FGFR tyrosine …

The coming of age of liquid biopsy in neuro-oncology

G Berzero, V Pieri, P Mortini, M Filippi, G Finocchiaro - Brain, 2023 - academic.oup.com
The clinical role of liquid biopsy in oncology is growing significantly. In gliomas and other
brain tumours, targeted sequencing of cell-free DNA (cfDNA) from CSF may help differential …

Immune checkpoint inhibitors for brain metastases in non-small-cell lung cancer: from rationale to clinical application

G Xiao, Z Liu, X Gao, H Wang, H Peng, J Li… - …, 2021 - Taylor & Francis
Brain metastases (BM) is common in non-small-cell lung cancer (NSCLC) patients. Immune
checkpoint inhibitors (ICIs) have gradually become a routine treatment for NSCLC BM …

[HTML][HTML] Molecular mechanisms driving the formation of brain metastases

BK Campbell, Z Gao, NM Corcoran, SS Stylli… - Cancers, 2022 - mdpi.com
Simple Summary Brain metastases are the most common brain tumor in adults and are
associated with poor prognosis. The propensity of different solid tumors to metastasize …