Hyperbaric oxygen treatment: effects on mitochondrial function and oxidative stress

N Schottlender, I Gottfried, U Ashery - Biomolecules, 2021 - mdpi.com
Hyperbaric oxygen treatment (HBOT)—the administration of 100% oxygen at atmospheric
pressure (ATA) greater than 1 ATA—increases the proportion of dissolved oxygen in the …

Therapeutic hypothermia in spinal cord injury: the status of its use and open questions

J Wang, DD Pearse - International journal of molecular sciences, 2015 - mdpi.com
Spinal cord injury (SCI) is a major health problem and is associated with a diversity of
neurological symptoms. Pathophysiologically, dysfunction after SCI results from the …

The role of therapeutic hypothermia after traumatic spinal cord injury—a systematic review

S Alkabie, AJ Boileau - World neurosurgery, 2016 - Elsevier
Background Traumatic spinal cord injury (SCI) is a devastating neurologic entity
characterized by a primary insult followed by a secondary pathologic cascade that …

Synergistic neuroprotective effects of hyperbaric oxygen and methylprednisolone following contusive spinal cord injury in rat

F Ahmadi, M Zargari, D Nasiry… - The Journal of Spinal …, 2022 - Taylor & Francis
Objective Recent studies revealed the neuroprotective effects of hyperbaric oxygen (HBO)
on spinal cord injury (SCI). Meanwhile, the use of methylprednisolone (MP) is one of the …

Hyperbaric oxygen therapy of spinal cord injury

NP Patel, JH Huang - Medical gas research, 2017 - journals.lww.com
Spinal cord injury (SCI) is a complex disease process that involves both primary and
secondary mechanisms of injury and can leave patients with devastating functional …

Mitochondrial division inhibitor 1 ameliorates mitochondrial injury, apoptosis, and motor dysfunction after acute spinal cord injury in rats

G Li, Z Jia, Y Cao, Y Wang, H Li, Z Zhang, J Bi… - Neurochemical …, 2015 - Springer
Abstract Mitochondrial division inhibitor 1 (Mdivi-1) is the most effective pharmacological
inhibitor of mitochondrial fission. Spinal cord injury (SCI) is a common and serious trauma …

Systematic review and meta-analysis of therapeutic hypothermia in animal models of spinal cord injury

PE Batchelor, P Skeers, A Antonic, TE Wills… - PloS one, 2013 - journals.plos.org
Background Therapeutic hypothermia is a clinically useful neuroprotective therapy for
cardiac arrest and neonatal hypoxic ischemic encephalopathy and may potentially be useful …

Imatinib inhibits oxidative stress response in spinal cord injury rats by activating Nrf2/HO‑1 signaling pathway Retraction in/10.3892/etm. 2023.12280

L Liu, J Zhou, Y Wang, T Qi… - Experimental and …, 2020 - spandidos-publications.com
Abstract Effect of imatinib on rats with spinal cord injury (SCI) was investigated through the
nuclear factor erythroid 2‑related factor 2 (Nrf2)/heme oxygenase‑1 (HO‑1) signaling …

Hypothermia for acute spinal cord injury

A Vedantam, AD Levi - Neurosurgery Clinics, 2021 - neurosurgery.theclinics.com
Spinal cord injury (SCI) can cause devastating motor, sensory, and autonomic deficits. The
treatment of acute SCI is aimed at preventing secondary injury and promoting neural repair …

Combination therapy with hyperbaric oxygen and erythropoietin inhibits neuronal apoptosis and improves recovery in rats with spinal cord injury

Y Zhou, P Su, Z Pan, D Liu, Y Niu, W Zhu… - Physical …, 2019 - academic.oup.com
Background Apoptosis plays an important role in various diseases, including spinal cord
injury (SCI). Hyperbaric oxygen (HBO) and erythropoietin (EPO) promote the recovery from …