Major advances in the chromatin and epigenetics fields have uncovered the importance of
core histones, histone variants and their post-translational modifications (PTMs) in …

Epigenetic regulation occurs on the level of compacting DNA into chromatin. The functional
unit of chromatin is the nucleosome, which consists of DNA wrapped around a core of …

Abstract Objective Rates of IgE‐mediated food allergy (FA) have increased over the last few
decades, and mounting evidence implicates disruption of epigenetic profiles in various …

Background Recently, many studies have been conducted to examine immune response
modification at epigenetic level, but the candidate effect of RNA 5‐methylcytosine (m5C) …

Purpose Oral squamous cell carcinoma (OSCC) is the most common oral cancer worldwide.
Pyroptosis is a type of programmed cell death mediated by caspase, accompanied by an …

Mutations in the nucleophosmin 1 (NPM1 mut) gene are the commonest molecular lesions
occurring in≥ 50% of cases with acute myeloid leukemia (AML) without cytogenetic …

Histone H1 is involved in the regulation of chromatin higher-order structure and compaction.
In humans, histone H1 is a multigene family with seven subtypes differentially expressed in …

Cytogenetic normal AML with NPM1 mutations forms a distinct AML entity, associated with
an intermediate prognosis and a heterogeneous response to treatment. We previously …

Analysis of chromatin remodelling in neoplastic stem cells as compared to ontogenetically
related neural stem cells, reveals multifactorial epigenetic regulation of signalling pathways …

Background It has been proved that DNA methylation, as an epigenetic regulatory mode,
plays a crucial role in the initiation, progression and invasion of hepatocellular carcinoma …