Diabetic cardiomyopathy is a result of diabetes-induced changes in the structure and
function of the heart. Hyperglycemia affects multiple pathways in the diabetic heart, but …

Sedentary life style and high calorie dietary habits are prominent leading cause of metabolic
syndrome in modern world. Obesity plays a central role in occurrence of various diseases …

Background: Brown adipose tissue (BAT) is an important tissue for thermogenesis, making it
a potential target to decrease the risks of obesity, type 2 diabetes, and cardiovascular …

Progressive accumulation of defective mitochondria is a common feature of aged cells.
SIRT3 is a NAD+-dependent protein deacetylase that regulates mitochondrial function and …

The metabolic syndrome is a constellation of metabolic disorders including obesity,
hypertension, and insulin resistance, components which are risk factors for the development …

Significance: Oxidative stress is a well established hallmark of cardiovascular disease and
there is strong evidence for a causal role of reactive oxygen and nitrogen species (RONS) …

One of the greatest examples of integrated signal transduction is revealed by examination of
effects mediated by AKT kinase in myocardial biology. Positioned at the intersection of …

A cDNA clone encoding a 64-amino acid type 3 metallothionein protein, designated
GhMT3a, was isolated from cotton (Gossypium hirsutum) by cDNA library screening …

Although advances in medical technology and health care have improved the early
diagnosis and management for cardiorenal metabolic disorders, the prevalence of obesity …

Obesity is an emerging problem worldwide. Hospitalized obese patients often have a worse
outcome than patients of normal weight, particularly in the setting of trauma and critical care …