miRNA: a promising therapeutic target in cancer
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …
complementarity pairing. Since discovery, they have been reported to be involved in a …
miRNAs: potential as biomarkers and therapeutic targets for cancer
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …
A systematic review of miR-29 in cancer
MicroRNAs (miRNA) are small non-coding RNAs (∼ 22 nt in length) that are known as
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …
Molecular mechanisms of drug resistance in ovarian cancer
L Norouzi‐Barough, MR Sarookhani… - Journal of cellular …, 2018 - Wiley Online Library
Ovarian cancer is the most lethal malignancy among the gynecological cancers, with a 5‐
year survival rate, mainly due to being diagnosed at advanced stages, recurrence and …
year survival rate, mainly due to being diagnosed at advanced stages, recurrence and …
miR-29c-3p inhibits autophagy and cisplatin resistance in ovarian cancer by regulating FOXP1/ATG14 pathway
Z Hu, M Cai, Y Zhang, L Tao, R Guo - Cell Cycle, 2020 - Taylor & Francis
Autophagy, characterized by the elevator of autophagy-related gene 14 (ATG14) and the
dysregulation of autophagy-related proteins, contributes to the cisplatin (DDP) resistance in …
dysregulation of autophagy-related proteins, contributes to the cisplatin (DDP) resistance in …
COL1A1: a novel oncogenic gene and therapeutic target in malignancies
X Li, X Sun, C Kan, B Chen, N Qu, N Hou, Y Liu… - … -Research and Practice, 2022 - Elsevier
Collagen type I alpha 1 (COL1A1), a member of the collagen family, is involved in epithelial–
mesenchymal transition, which is closely linked to malignant tumorigenesis. COL1A1 is …
mesenchymal transition, which is closely linked to malignant tumorigenesis. COL1A1 is …
[HTML][HTML] COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway
Z Zhang, Y Wang, J Zhang… - Molecular Medicine …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is the third leading cause of cancer‑associated mortality, and is a
major health problem. Collagen type I α 1 (COL1A1) is a major component of collagen type I …
major health problem. Collagen type I α 1 (COL1A1) is a major component of collagen type I …
Targeting type I collagen for cancer treatment
R Shi, Z Zhang, A Zhu, X Xiong, J Zhang… - … Journal of Cancer, 2022 - Wiley Online Library
Collagen is the most abundant protein in animals. Interactions between tumor cells and
collagen influence every step of tumor development. Type I collagen is the main fibrillar …
collagen influence every step of tumor development. Type I collagen is the main fibrillar …
MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells
M Moghbeli - Journal of ovarian research, 2021 - Springer
Background Ovarian cancer (OC) is one of the leading causes of cancer related deaths
among women. Due to the asymptomatic tumor progression and lack of efficient screening …
among women. Due to the asymptomatic tumor progression and lack of efficient screening …
[HTML][HTML] Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles
Y Yan, C Du, X Duan, X Yao, J Wan, Z Jiang… - … pharmaceutica Sinica B, 2022 - Elsevier
The lung is one of the most common sites for cancer metastasis. Collagens in the lung
provide a permissive microenvironment that supports the colonization and outgrowth of …
provide a permissive microenvironment that supports the colonization and outgrowth of …