A multimodal cell census and atlas of the mammalian primary motor cortex

Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …

Chronic, cortex-wide imaging of specific cell populations during behavior

J Couto, S Musall, XR Sun, A Khanal, S Gluf… - Nature protocols, 2021 - nature.com
Measurements of neuronal activity across brain areas are important for understanding the
neural correlates of cognitive and motor processes such as attention, decision-making and …

[HTML][HTML] Cellular anatomy of the mouse primary motor cortex

R Muñoz-Castañeda, B Zingg, KS Matho, X Chen… - Nature, 2021 - nature.com
An essential step toward understanding brain function is to establish a structural framework
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …

Genetically identified amygdala–striatal circuits for valence-specific behaviors

X Zhang, W Guan, T Yang, A Furlan, X Xiao, K Yu… - Nature …, 2021 - nature.com
The basolateral amygdala (BLA) plays essential roles in behaviors motivated by stimuli with
either positive or negative valence, but how it processes motivationally opposing information …

Decoding mixed messages in the developing cortex: translational regulation of neural progenitor fate

ML Hoye, DL Silver - Current opinion in neurobiology, 2021 - Elsevier
Highlights•Neural progenitors are transcriptionally primed to generate diverse cortical cell
types.•Post-transcriptional control of progenitors and neurons fine tunes cell fate …

Comprehensive dual-and triple-feature intersectional single-vector delivery of diverse functional payloads to cells of behaving mammals

LE Fenno, C Ramakrishnan, YS Kim, KE Evans, M Lo… - Neuron, 2020 - cell.com
The resolution and dimensionality with which biologists can characterize cell types have
expanded dramatically in recent years, and intersectional consideration of such features (eg …

Pyramidal cell types drive functionally distinct cortical activity patterns during decision-making

S Musall, XR Sun, H Mohan, X An, S Gluf, SJ Li… - Nature …, 2023 - nature.com
Understanding how cortical circuits generate complex behavior requires investigating the
cell types that comprise them. Functional differences across pyramidal neuron (PyN) types …

Neuron class–specific responses govern adaptive myelin remodeling in the neocortex

SM Yang, K Michel, V Jokhi, E Nedivi, P Arlotta - Science, 2020 - science.org
INTRODUCTION Myelin is a fundamental structure in the vertebrate nervous system, and its
precise formation and regulation are critical for complex neuronal function, including …

Molecular, spatial and projection diversity of neurons in primary motor cortex revealed by in situ single-cell transcriptomics

M Zhang, SW Eichhorn, B Zingg, Z Yao, H Zeng… - BioRxiv, 2020 - biorxiv.org
A mammalian brain is comprised of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing provides a powerful approach to …

[HTML][HTML] The lamprey forebrain–evolutionary implications

SM Suryanarayana, J Pérez-Fernández… - Brain Behavior and …, 2021 - karger.com
The forebrain plays a critical role in a broad range of neural processes encompassing
sensory integration and initiation/selection of behaviour. The forebrain functions through an …