Reactive oxygen species scavenging nanomedicine for the treatment of ischemic heart disease

Z Zhang, R Dalan, Z Hu, JW Wang… - Advanced …, 2022 - Wiley Online Library
Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Effects of aircraft noise cessation on blood pressure, cardio-and cerebrovascular endothelial function, oxidative stress, and inflammation in an experimental animal …

MTB Jimenez, A Gericke, K Frenis, S Rajlic… - Science of the Total …, 2023 - Elsevier
Large epidemiological studies have shown that traffic noise promotes the development of
cardiometabolic diseases. It remains to be established how long these adverse effects of …

Oxidative stress in arterial hypertension (HTN): The nuclear factor erythroid factor 2-related factor 2 (Nrf2) pathway, implications and future perspectives

DM Tanase, AG Apostol, CF Costea, CC Tarniceriu… - Pharmaceutics, 2022 - mdpi.com
Arterial hypertension (HTN) is one of the most prevalent entities globally, characterized by
increased incidence and heterogeneous pathophysiology. Among possible etiologies …

Gentisic acid protects against diabetic nephropathy in Nicotinamide-Streptozotocin administered male mice by attenuating oxidative stress and inflammation: The role …

RN Razliqi, A Ahangarpour, SA Mard… - Chemico-Biological …, 2023 - Elsevier
Oxidative stress and inflammation play a pivotal role in the pathogenesis of diabetic
nephropathy (DN). Local renin-angiotensin systems (RAS) contribute to the pathogenesis …

Effects of resveratrol on vascular function in retinal ischemia-reperfusion injury

P Chronopoulos, C Manicam, JK Zadeh, P Laspas… - Antioxidants, 2023 - mdpi.com
Ischemia-reperfusion (I/R) events are involved in the development of various ocular
pathologies, eg, retinal artery or vein occlusion. We tested the hypothesis that resveratrol is …

Sulodexide prevents hyperglycemia-induced endothelial dysfunction and oxidative stress in porcine retinal arterioles

A Dauth, A Bręborowicz, Y Ruan, Q Tang, JK Zadeh… - Antioxidants, 2023 - mdpi.com
Diabetes mellitus may cause severe damage to retinal blood vessels. The central aim of this
study was to test the hypothesis that sulodexide, a mixture of glycosaminoglycans, has a …

Anti-oxidant and pro-oxidant effects of peroxiredoxin 6: A potential target in respiratory diseases

W Jia, C Dong, B Li - Cells, 2023 - mdpi.com
Peroxiredoxin 6 (PRDX6) is widely distributed in several organs, especially the lungs. The
role of PRDX6 in oxidative stress is controversial and even contradictory, as indicated by …

Hypertension facilitates age-related diseases.~ Is hypertension associated with a wide variety of diseases?~

M Mogi, Y Ikegawa, S Haga, S Hoshide… - Hypertension Research, 2024 - nature.com
Hypertension, a disease whose prevalence increases with age, induces pathological
conditions of ischemic vascular disorders such as cerebral infarction and myocardial …

High-fat diet causes endothelial dysfunction in the mouse ophthalmic artery

S Jiang, N Xia, F Buonfiglio, EW Böhm, Q Tang… - Experimental Eye …, 2024 - Elsevier
Obesity is a significant health concern that leads to impaired vascular function and
subsequent abnormalities in various organs. The impact of obesity on ocular blood vessels …