Epithelial-mesenchymal transition (EMT): the type-2 EMT in wound healing, tissue regeneration and organ fibrosis

GD Marconi, L Fonticoli, TS Rajan, SD Pierdomenico… - Cells, 2021 - mdpi.com
The epithelial–mesenchymal transition (EMT) is an essential event during cell development,
in which epithelial cells acquire mesenchymal fibroblast-like features including reduced …

Functional relationship between osteogenesis and angiogenesis in tissue regeneration

F Diomede, GD Marconi, L Fonticoli… - International Journal of …, 2020 - mdpi.com
Bone tissue renewal can be outlined as a complicated mechanism centered on the
interaction between osteogenic and angiogenic events capable of leading to bone formation …

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Periodontal ligament stem cells: current knowledge and future perspectives

O Trubiani, J Pizzicannella, S Caputi… - Stem cells and …, 2019 - liebertpub.com
Teeth represent a fascinating area of study in regenerative medicine, because of their
unique and complex developmental origin. Several types of mesenchymal stem cells …

Oral bone tissue regeneration: mesenchymal stem cells, secretome, and biomaterials

A Gugliandolo, L Fonticoli, O Trubiani… - International journal of …, 2021 - mdpi.com
In the last few decades, tissue engineering has become one of the most studied medical
fields. Even if bone shows self-remodeling properties, in some cases, due to injuries or …

Dental stem cell‐derived secretome/conditioned medium: The future for regenerative therapeutic applications

S El Moshy, IA Radwan, D Rady… - Stem Cells …, 2020 - Wiley Online Library
Regenerative medicine literature has proposed mesenchymal stem/progenitor cell‐(MSC‐)
mediated therapeutic approaches for their great potential in managing various diseases and …

Dental stem cell-derived extracellular vesicles as promising therapeutic agents in the treatment of diseases

Y Li, X Duan, Y Chen, B Liu, G Chen - International Journal of Oral …, 2022 - nature.com
Dental stem cells (DSCs), an important source of mesenchymal stem cells (MSCs), can be
easily obtained by minimally invasive procedures and have been used for the treatment of …

Dental pulp stem cell-derived secretome and its regenerative potential

JK Bar, A Lis-Nawara, PG Grelewski - International journal of molecular …, 2021 - mdpi.com
The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …

Human oral stem cells, biomaterials and extracellular vesicles: a promising tool in bone tissue repair

O Trubiani, GD Marconi, SD Pierdomenico… - International Journal of …, 2019 - mdpi.com
Tissue engineering and/or regenerative medicine are fields of life science exploiting both
engineering and biological fundamentals to originate new tissues and organs and to induce …

Engineered extracellular vesicles from human periodontal-ligament stem cells increase VEGF/VEGFR2 expression during bone regeneration

J Pizzicannella, A Gugliandolo, T Orsini… - Frontiers in …, 2019 - frontiersin.org
Bone regeneration represents still a challenge, in particular for calvarium defects. Recently,
the development of biomaterials with the addiction of stem cells is giving promising results …