A narrative systematic review of the clinical utility of cycle threshold values in the context of COVID-19

SN Rao, D Manissero, VR Steele, J Pareja - Infectious diseases and …, 2020 - Springer
Background The ability to predict likely prognosis and infectiousness for patients with COVID-
19 would aid patient management decisions. Diagnosis is usually via real-time PCR, and it …

Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children

P Zimmermann, N Curtis - The Pediatric infectious disease journal, 2020 - journals.lww.com
Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA
viruses. Four CoVs commonly circulate among humans: HCoV2-229E,-HKU1,-NL63 and …

Mechanisms in endocrinology: vitamin D and COVID-19

JP Bilezikian, D Bikle, M Hewison… - European journal of …, 2020 - academic.oup.com
The SARS-CoV-2 virus responsible for the COVID-19 pandemic has generated an explosion
of interest both in the mechanisms of infection leading to dissemination and expression of …

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort …

KKW To, OTY Tsang, WS Leung, AR Tam… - The Lancet infectious …, 2020 - thelancet.com
Summary Background Coronavirus disease 2019 (COVID-19) causes severe community
and nosocomial outbreaks. Comprehensive data for serial respiratory viral load and serum …

Saliva: potential diagnostic value and transmission of 2019-nCoV

R Xu, B Cui, X Duan, P Zhang, X Zhou… - International journal of …, 2020 - nature.com
nCoV epidemic was firstly reported at late December of 2019 and has caused a global
outbreak of COVID-19 now. Saliva, a biofluid largely generated from salivary glands in oral …

Viral dynamics and real-time RT-PCR Ct values correlation with disease severity in COVID-19

AA Rabaan, R Tirupathi, AA Sule, J Aldali, AA Mutair… - Diagnostics, 2021 - mdpi.com
Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease
2019 (COVID-19). However, many scientists disagree, and it is essential to understand that …

Risk factors for mortality among COVID-19 patients

O Albitar, R Ballouze, JP Ooi, SMS Ghadzi - Diabetes research and clinical …, 2020 - Elsevier
Aims COVID-19 is a current global pandemic. However, comprehensive global data
analyses for its mortality risk factors are lacking. The current investigation aimed to assess …

[HTML][HTML] ACE2, much more than just a receptor for SARS-COV-2

L Samavati, BD Uhal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The rapidly evolving pandemic of severe acute respiratory syndrome coronavirus (SARS-
CoV-2) infection worldwide cost many lives. The angiotensin converting enzyme-2 (ACE-2) …

Viral dynamics in mild and severe cases of COVID-19

Y Liu, LM Yan, L Wan, TX Xiang, A Le… - The Lancet infectious …, 2020 - thelancet.com
(A) DCT values (Ctsample-Ctref) from patients with mild and severe COVID-19 at different
stages of disease onset. Median, quartile 1, and quartile 3 are shown.(B) DCT values of …

Coronavirus disease 2019 (COVID‐19) and cardiovascular disease: a viewpoint on the potential influence of angiotensin‐converting enzyme inhibitors/angiotensin …

J Guo, Z Huang, L Lin, J Lv - Journal of the American Heart …, 2020 - Am Heart Assoc
According to available clinical data,≈ 15% to 30% of the COVID-19 patients are with
hypertension and≈ 2.5% to 15% are with coronary heart disease. 3–5 …