Network structure of the master clock is important for its primary function

C Gu, J Li, J Zhou, H Yang, J Rohling - Frontiers in Physiology, 2021 - frontiersin.org
A master clock located in the suprachiasmatic nucleus (SCN) regulates the circadian rhythm
of physiological and behavioral activities in mammals. The SCN has two main functions in …

Random heterogeneity outperforms design in network synchronization

Y Zhang, JL Ocampo-Espindola… - Proceedings of the …, 2021 - National Acad Sciences
A widely held assumption on network dynamics is that similar components are more likely to
exhibit similar behavior than dissimilar ones and that generic differences among them are …

Formation of recurring transient Ca2+-based intercellular communities during Drosophila hematopoiesis

SB David, KYL Ho, G Tanentzapf… - Proceedings of the …, 2024 - National Acad Sciences
Tissue development occurs through a complex interplay between many individual cells. Yet,
the fundamental question of how collective tissue behavior emerges from heterogeneous …

Mechanism for strong chimeras

Y Zhang, AE Motter - Physical review letters, 2021 - APS
Chimera states have attracted significant attention as symmetry-broken states exhibiting the
unexpected coexistence of coherence and incoherence. Despite the valuable insights …

Approaching the molecular origins of collective dynamics in oscillating cell populations

P Mehta, T Gregor - Current opinion in genetics & development, 2010 - Elsevier
From flocking birds, to organ generation, to swarming bacterial colonies, biological systems
often exhibit collective behaviors. Here, we review recent advances in our understanding of …

Measuring relative coupling strength in circadian systems

C Schmal, ED Herzog, H Herzel - Journal of biological …, 2018 - journals.sagepub.com
Modern imaging techniques allow the monitoring of circadian rhythms of single cells.
Coupling between these single cellular circadian oscillators can generate coherent periodic …

Effect of network architecture on synchronization and entrainment properties of the circadian oscillations in the suprachiasmatic nucleus

M Hafner, H Koeppl, D Gonze - PLoS computational biology, 2012 - journals.plos.org
In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus constitutes the central
circadian pacemaker. The SCN receives light signals from the retina and controls peripheral …

Entrainment of peripheral clock genes by cortisol

PD Mavroudis, JD Scheff, SE Calvano… - Physiological …, 2012 - journals.physiology.org
Circadian rhythmicity in mammals is primarily driven by the suprachiasmatic nucleus (SCN),
often called the central pacemaker, which converts the photic information of light and dark …

From intracellular signaling to population oscillations: bridging size‐and time‐scales in collective behavior

AE Sgro, DJ Schwab, J Noorbakhsh… - Molecular systems …, 2015 - embopress.org
Collective behavior in cellular populations is coordinated by biochemical signaling networks
within individual cells. Connecting the dynamics of these intracellular networks to the …

Synchronization and entrainment of coupled circadian oscillators

N Komin, AC Murza, E Hernández-García… - Interface …, 2011 - royalsocietypublishing.org
Circadian rhythms in mammals are controlled by the neurons located in the suprachiasmatic
nucleus of the hypothalamus. In physiological conditions, the system of neurons is very …