The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …

Tuberculosis (TB), also known as the “White Plague”, is caused by Mycobacterium
tuberculosis (Mtb). Before the COVID-19 epidemic, TB had the highest mortality rate of any …

Macrophages play an essential role in the early immune response to Mycobacterium
tuberculosis and are the cell type preferentially infected in vivo. Primary macrophages and …

Polyethylene glycol (PEG) is a common ingredient in nanomedicines and pharmaceuticals.
Recent studies show that approximately 20–70% of humans have anti-PEG antibodies that …

The outcome of Mycobacterium tuberculosis infection and the immunological response to
the bacillus Calmette-Guerin (BCG) vaccine are highly variable in humans. Deciphering the …

It is generally thought that Mycobacterium tuberculosis (Mtb)-specific CD4+ Th1 cells
producing IFN-γ are essential for protection against tuberculosis (TB). In some studies …

Abstract Live attenuated Bacille Calmette–Guerin (BCG) bacillus is the only licensed
vaccine for tuberculosis prevention worldwide to date. It must be delivered intradermally to …

Th1 lymphocytes are considered the main mediators of protection against tuberculosis (TB);
however, their phenotypic characteristics and relationship with Th17 and Th1Th17 …

Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, is one of
the top ten infectious diseases worldwide, and is the leading cause of morbidity from a …

Therapeutic vaccines have promise as adjunctive treatment for tuberculosis (TB) or as
preventives against TB relapse. An important development challenge is the limited …