Purpose Cancer-induced muscle wasting (ie, cancer cachexia, CC) is a common and
devastating syndrome that results in the death of more than 1 in 5 patients. Although …

Cancer cachexia is defined as a multi‐factorial syndrome characterised by an ongoing loss
of skeletal muscle mass and progressive functional impairment, estimated to affect 50–80 …

(1) Background: Exercise exerts many neuroprotective effects in diabetes-induced brain
disorders. In this study, we investigated the effect of high-intensity interval training (HIIT) on …

Abstract Background Type 2 diabetes (T2D) leads to serious respiratory problems. This
study investigated the effectiveness of high-intensity interval training (HIIT) on T2D-induced …

Apoptotic signaling pathways are involved in acute kidney injury (AKI) induced by the
antineoplastic drug cisplatin (Cis). Mechanical stress is known to increase interleukin (IL) …

This study investigated the effects of pentoxifylline (PTX), high intensity interval training
(HIIT) and moderate intensity continuous training (MICT) separately and in combination, on …

Background Testicular germ cell tumors (TGCTs) represent∼ 95% of testicular malignancies
and are the most common type of malignancy in young male adults. While the incidence of …

Skeletal muscle atrophy is an important characteristic of cachexia, which can be induced by
chemotherapy and significantly contributes to functional muscle impairment. Inflammation …

Cisplatin is widely used as an anti-neoplastic agent but is limited by its nephrotoxicity. The
use of mesenchymal stem cells (MSCs) for the management of acute kidney injury (AKI) …

Cisplatin is an effective antineoplastic agent, but its use is limited by its nephrotoxicity
caused by the oxidative stress in tubular epithelium of nephrons. On the other hand, regular …