Potassium (K+) channels are highly regulated membrane proteins that control the potassium
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …

Pharmacological targeting of mitochondrial ion channels is emerging as a promising
approach to eliminate cancer cells; as most of these channels are differentially expressed …

Oxidative stress and immune response play an important role in the development of several
cancers, including melanoma. Ion channels are aberrantly expressed in tumour cells and …

Ion channels are key regulators of cancer cell pathophysiology. They contribute to a variety
of processes such as maintenance of cellular osmolarity and membrane potential, motility …

The field of mitochondrial ion channels underwent a rapid development during the last
decade, thanks to the molecular identification of some of the nuclear-encoded organelle …

Mitochondria are bioenergetic organelles with a plethora of fundamental functions ranging
from metabolism and ATP production to modulation of signaling events leading to cell …

In this paper, the current challenges of mitochondrial potassium channels research were
critically reviewed. Even though recent progress in understanding K+ traffic in mitochondria …

The field of mitochondrial ion channels has undergone a rapid development during the last
three decades, due to the molecular identification of some of the channels residing in the …

Plasma membrane potassium channels importantly contribute to maintain ion homeostasis
across the cell membrane. The view is emerging that also those residing in intracellular …

TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5,
are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is …