Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

Lung cancer is the leading cause of cancer-related deaths worldwide, with non-small cell
lung cancer (NSCLC) being the predominant histological subtype. Despite the emergence of …

Background Lung adenocarcinoma (LUAD) is the most prevalent subtype of non-small cell
lung cancer. Additionally, disulfidptosis, a newly discovered type of cell death, has been …

Mast cells are derived from hematopoietic stem cell precursors and are essential to the
genesis and manifestations of the allergic response. Activation of these cells by allergens …

Abstract Multi-target Tyrosine Kinase Inhibitors (MTKIs) have drawn substantial attention in
tumor therapy. MTKIs could inhibit tumor cell proliferation and induce apoptosis by blocking …

Aptamers are single-stranded DNA or RNA oligomers that have the ability to generate
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …

Thyroid cancers (TCs) are the most common tumors of the endocrine system and a constant
rise in the number of TC cases has been observed for the past few decades. TCs are one of …

Kinase inhibitors (KIs) represent a growing class of drugs directed at various protein kinases
and used in the treatment of both solid tumors and hematologic malignancies. It is a …

Ascorbate (vitamin C in primates) functions as a cofactor for a number of enzymatic reactions
represented by prolyl hydroxylases and as an antioxidant due to its ability to donate …

In this review article, we will first provide a brief overview of EGF receptor (EGFR) structure
and function, and its importance as a therapeutic target in epithelial carcinomas. We will …