Sickle cell disease (SCD) is an inherited monogenic disorder with high prevalence
throughout sub-Saharan Africa, the Mediterranean basin, the Middle East, and India …

Thalassemia is a genetic haematological disorder that arises due to defects in the α and β‑
globin genes. Worldwide, 0.3‑0.4 million children are born with haemoglobinopathies per …

Objectives: To investigate trends in hemoglobinopathies following the establishment of a
mandatory premarital screening program (MPMSP) in the southern region of Saudi Arabia …

BACKGROUND: Thalassemia is considered as the most common single gene disorder
worldwide. Preventive measures include identification of thalassemia carriers (traits) through …

Sickle cell disease is associated with progressive and increased neurological morbidity
throughout the lifespan. In people with sickle cell anaemia (the most common and severe …

Hydroxyl radicals (OH.) are one of the most active reactive oxidants recognized for their
deleterious effects to cause protein oxidative damage. Thymoquinone, a monoterpene …

Methods: A descriptive cross-sectional study was conducted among the Tharu population in
the Department of General Medicine of a secondary care centre from 10 January 2020 to 10 …

Recent studies have indicated that microRNA and VEGF are considered to be genetic
modifiers and are associated with elevated levels of fetal haemoglobin HbF, and thus they …

Background: One of the most prevalent genetic disorders and major problems in Pakistan is
hemoglobinopathies. Every year, 5,000 additional patients are added to the pool …

Las hemoglobinopatías son enfermedades genéticas que afectan la producción o estructura
de la hemoglobina, la proteína que transporta el oxígeno en los glóbulos rojos. Las …