Preterm brain injury, antenatal triggers, and therapeutics: timing is key
DRMG Ophelders, R Gussenhoven, L Klein… - Cells, 2020 - mdpi.com
With a worldwide incidence of 15 million cases, preterm birth is a major contributor to
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …
Neonatal encephalopathy: Etiologies other than hypoxic-ischemic encephalopathy
AGS Karamian, S Mercimek-Andrews… - Seminars in Fetal and …, 2021 - Elsevier
Neonatal encephalopathy (NE) describes the clinical syndrome of a newborn with abnormal
brain function that may result from a variety of etiologies. HIE should be distinguished from …
brain function that may result from a variety of etiologies. HIE should be distinguished from …
Novel interventions to reduce oxidative-stress related brain injury in neonatal asphyxia
AL Solevåg, GM Schmölzer, PY Cheung - Free Radical Biology and …, 2019 - Elsevier
Perinatal asphyxia-induced brain injury may present as hypoxic-ischemic encephalopathy in
the neonatal period, and disability including cerebral palsy in the long term. The brain injury …
the neonatal period, and disability including cerebral palsy in the long term. The brain injury …
Animal models for neonatal brain injury induced by hypoxic ischemic conditions in rodents
Neonatal hypoxia-ischemia and resulting encephalopathies are of significant concern.
Intrapartum asphyxia is a leading cause of neonatal death globally. Among surviving infants …
Intrapartum asphyxia is a leading cause of neonatal death globally. Among surviving infants …
Management of multi organ dysfunction in neonatal encephalopathy
Neonatal Encephalopathy (NE) describes neonates with disturbed neurological function in
the first post-natal days of life. NE is an overall term that does not specify the etiology of the …
the first post-natal days of life. NE is an overall term that does not specify the etiology of the …
White matter injury in the neonatal hypoxic‐ischemic brain and potential therapies targeting microglia
R Shao, D Sun, Y Hu, D Cui - Journal of Neuroscience …, 2021 - Wiley Online Library
Neonatal hypoxic–ischemic (H‐I) injury, which mainly causes neuronal damage and white
matter injury (WMI), is among the predominant causes of infant morbidity (cerebral palsy …
matter injury (WMI), is among the predominant causes of infant morbidity (cerebral palsy …
Current therapies for neonatal hypoxic–ischaemic and infection-sensitised hypoxic–ischaemic brain damage
K Tetorou, C Sisa, A Iqbal, K Dhillon… - Frontiers in synaptic …, 2021 - frontiersin.org
Neonatal hypoxic–ischaemic brain damage is a leading cause of child mortality and
morbidity, including cerebral palsy, epilepsy, and cognitive disabilities. The majority of …
morbidity, including cerebral palsy, epilepsy, and cognitive disabilities. The majority of …
Temporal Characterization of Microglia‐Associated Pro‐and Anti‐Inflammatory Genes in a Neonatal Inflammation‐Sensitized Hypoxic‐Ischemic Brain Injury Model
ME Bernis, Y Schleehuber, M Zweyer… - Oxidative medicine …, 2022 - Wiley Online Library
Hypoxic‐ischemic encephalopathy (HIE) mainly affects preterm and term newborns, leading
to a high risk of brain damage. Coexisting infection/inflammation and birth asphyxia are key …
to a high risk of brain damage. Coexisting infection/inflammation and birth asphyxia are key …
Unanswered questions regarding therapeutic hypothermia for neonates with neonatal encephalopathy
Therapeutic hypothermia (TH) is now well established to improve intact survival after
neonatal encephalopathy (NE). However, many questions could not be addressed by the …
neonatal encephalopathy (NE). However, many questions could not be addressed by the …
Neonatal encephalopathy with group B streptococcal disease worldwide: systematic review, investigator group datasets, and meta-analysis
CJ Tann, KA Martinello, S Sadoo… - Clinical Infectious …, 2017 - academic.oup.com
Background Neonatal encephalopathy (NE) is a leading cause of child mortality and longer-
term impairment. Infection can sensitize the newborn brain to injury; however, the role of …
term impairment. Infection can sensitize the newborn brain to injury; however, the role of …