Effect of xanthophyll-rich food and supplement intake on visual outcomes in healthy adults and those with eye disease: a systematic review, meta-analysis, and meta …

W Hu, P Shankar, Y Yao, X Su, JE Kim - Nutrition Reviews, 2024 - academic.oup.com
Context Xanthophyll intake is known to improve eye health; however, its benefits on visual
outcomes have not been systematically studied, particularly in a population with eye …

Review of clinical approaches in fluorescence lifetime imaging ophthalmoscopy

L Sauer, KM Andersen, C Dysli… - … of biomedical optics, 2018 - spiedigitallibrary.org
Autofluorescence-based imaging techniques have become very important in the
ophthalmological field. Being noninvasive and very sensitive, they are broadly used in …

Fluorescence lifetime imaging ophthalmoscopy: a novel way to assess macular telangiectasia type 2

L Sauer, RH Gensure, M Hammer, PS Bernstein - Ophthalmology Retina, 2018 - Elsevier
Purpose Macular telangiectasia type 2 (MacTel) is an uncommon, late-onset complex retinal
disease that leads to central vision loss. No causative gene (s) have been identified to date …

[HTML][HTML] Fluorescence lifetime imaging ophthalmoscopy (FLIO) of macular pigment

L Sauer, KM Andersen, B Li… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: To describe different patterns of macular pigment (MP) seen in fluorescence
lifetime imaging ophthalmoscopy (FLIO) and to analyze ex vivo fluorescence characteristics …

[HTML][HTML] The emerging roles of the macular pigment carotenoids throughout the lifespan and in prenatal supplementation

PS Bernstein, R Arunkumar - Journal of lipid research, 2021 - ASBMB
Since the publication of the Age-Related Eye Disease Study 2 (AREDS2) in 2013, the
macular pigment carotenoids lutein (L) and zeaxanthin (Z) have become well known to both …

[HTML][HTML] Correlations between macular, skin, and serum carotenoids

CD Conrady, JP Bell, BM Besch… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: Ocular and systemic measurement and imaging of the macular carotenoids lutein
and zeaxanthin have been employed extensively as potential biomarkers of AMD risk. In this …

[HTML][HTML] Effect of Antioxidant Supplementation on Macular Pigment Optical Density and Visual Functions: A systematic review and network meta-analysis of …

W Hu, V Seah, V Huang, JE Kim - Advances in Nutrition, 2024 - Elsevier
Context Antioxidants are bioactive molecules that function to scavenge free radicals and
balance oxidative stress. While all antioxidants can act as reactive oxygen species …

Ocular carotenoid status in health and disease

L Sauer, B Li, PS Bernstein - Annual Review of Nutrition, 2019 - annualreviews.org
Retinal carotenoids are dietary nutrients that uniquely protect the eye from light damage and
various retinal pathologies. Their antioxidative properties protect the eye from many retinal …

Crystalline retinopathy: unifying pathogenic pathways of disease

JL Kovach, H Isildak, D Sarraf - Survey of ophthalmology, 2019 - Elsevier
Crystalline retinopathies may be associated with different etiologies including genetic, toxic,
degenerative, idiopathic, and iatrogenic causes. We outline the various types of crystalline …

[HTML][HTML] Why is zeaxanthin the most concentrated xanthophyll in the central fovea?

J Widomska, JP SanGiovanni, WK Subczynski - Nutrients, 2020 - mdpi.com
Diet-based xanthophylls (zeaxanthin and lutein) are conditionally essential polar
carotenoids preferentially accreted in high concentrations (1 mM) to the central retina, where …