High mobility group box 1 (HMGB1), a crucial proinflammatory cytokine, was reported to
activate the absent in melanoma 2 (AIM2) inflammasome, which are both essential in acute …

Soluble aggregates of the microtubule-associated protein tau have been challenging to
assemble and characterize, despite their important role in the development of tauopathies …

Various pattern recognition receptors (PRRs), including toll-like receptors (TLRs), play a
crucial role in recognizing invading pathogens as well as damage-associated molecular …

Chemotherapy-induced peripheral neuropathy (CIPN), one of major dose-limiting side
effects of first-line chemotherapeutic agents such as paclitaxel, oxaliplatin, vincristine, and …

Inflammation plays a central role in the development of asthma, which is considered an
allergic disease with a classic Th2 inflammatory profile. However, cytokine IL-17 has been …

Acute lung injury (ALI) is clinically characterized by excessive inflammation leading to acute
respiratory distress syndrome (ARDS), having high morbidity and mortality both in human …

Acute lung injury (ALI) is a complex syndrome with sepsis occurring in critical patients, who
usually lack effective therapy. Nuciferine is a primary bioactive component extracted from the …

Inflammation associated with acute respiratory distress syndrome (ARDS) can damage the
alveolar epithelium and surfactant and worsen the respiratory failure. Glucocorticoids (GC) …

A population of neutrophils recruited into cystic fibrosis (CF) airways is associated with
proteolytic lung damage, exhibiting high expression of primary granule exocytosis marker …

High-mobility group box 1 protein (HMGB1) is a crucial proinflammatory cytokine that
contributes to acute lung injury (ALI). Macrophages are known to express the primary …