Worldwide use of RUCAM for causality assessment in 81,856 idiosyncratic DILI and 14,029 HILI cases published 1993–mid 2020: a comprehensive analysis

R Teschke, G Danan - Medicines, 2020 - mdpi.com
Background: A large number of idiosyncratic drug induced liver injury (iDILI) and herb
induced liver injury (HILI) cases of variable quality has been published but some are a …

Idiosyncratic DILI: Analysis of 46,266 cases assessed for causality by RUCAM and published from 2014 to early 2019

R Teschke - Frontiers in pharmacology, 2019 - frontiersin.org
One of the most difficult challenges in clinical hepatology is the diagnosis of a drug-induced
liver injury (DILI). The timing of the events, exclusion of alternative causes, and taking into …

Treatment of drug-induced liver injury

R Teschke - Biomedicines, 2022 - mdpi.com
Current pharmacotherapy options of drug-induced liver injury (DILI) remain under
discussion and are now evaluated in this analysis. Needless to say, the use of the offending …

[HTML][HTML] Drug-induced liver injury and COVID-19: A review for clinical practice

GX Ortiz, G Lenhart, MW Becker… - World journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) consists of a systemic disease that can
present many complications. The infection presents broad clinical symptoms and a high rate …

[HTML][HTML] Causality imputation between herbal products and HILI: An algorithm evaluation in a systematic review

PF Soares, MTCF Fernandes, A de Santana Souza… - Annals of …, 2021 - Elsevier
Algorithms can have several purposes in the clinical practice. There are different scales for
causality imputation in DILI (Drug-Induced Liver Injury), but the applicability and validity of …

Evaluation of adverse drug reactions in paediatric patients: a retrospective study in Turkish hospital

Z Khan, Y Karataş, O Kıroğlu - Frontiers in pharmacology, 2021 - frontiersin.org
Drug safety in paediatric patients is a serious public health concern around the world. The
paediatric patients are more prone to adverse drug reactions (ADRs) than adults. Moreover …

[HTML][HTML] Efficacy of artificial liver support system in severe immune-associated hepatitis caused by camrelizumab: A case report and review of the literature

YW Tan, L Chen, XB Zhou - World Journal of Clinical Cases, 2021 - ncbi.nlm.nih.gov
Efficacy of artificial liver support system in severe immune-associated hepatitis caused by
camrelizumab: A case report and review of the literature - PMC Back to Top Skip to main content …

Role of liver biopsy in the era of clinical prediction scores for “drug-induced liver injury”(DILI): experience of a tertiary referral hospital

P Costa-Moreira, R Gaspar, P Pereira, S Lopes… - Virchows Archiv, 2020 - Springer
The clinical implications of the biopsy findings in cases of drug-induced liver injury (DILI) are
not fully elucidated. The aim of this study was to evaluate the histopathological findings of …

Injúria Hepática Induzida por Medicamentos em Pacientes Hospitalizados

ST Gonçalves, E Louro, RB Pedroso… - Research, Society and …, 2021 - rsdjournal.org
Objective: To conduct a literature review to identify which drugs cause the most drug
induced liver injury (DILI) in hospitalized patients. Methodology: A literature review was …

[HTML][HTML] A narrative review of herb-induced liver injury

TP Lee - Digestive Medicine Research, 2021 - dmr.amegroups.org
Herb and herbal product have been used for both healthy and specific ailments. Its use as
medicine or dietary supplements has increased worldwide for more than a decade due to …