Compared to conventional photon-based external beam radiation (PhXRT), carbon ion
radiotherapy (CIRT) has superior dose distribution, higher linear energy transfer (LET), and …

An understanding of proton radiobiology is critical for optimization of both proton
radiotherapy and assessment of carcinogenesis risk from space radiation. Although the …

Purpose The biological optimization of proton therapy can be achieved only through a
detailed evaluation of relative biological effectiveness (RBE) variations along the full range …

Radiotherapy for the treatment of cancer is undergoing an evolution, shifting to the use of
heavier ion species. For a plethora of malignancies, current radiotherapy using photons or …

It has been known for about sixty years that proton and heavy ion therapy is a very powerful
radiation procedure for treating tumors. It has an innate ability to irradiate tumors with greater …

A proposal for using cost-benefit analysis to evaluate the socioeconomic impact of public
investment in large scientific projects. Large particle accelerators, outer space probes …

Increasing use of heavy ions for cancer therapy and concerns from exposure to heavy
charged particles in space necessitate the study of the basic biological mechanisms …

Superb biological effectiveness and dose conformity represent a rationale for heavy-ion
therapy, which has thus far achieved good cancer controllability while sparing critical normal …

The lack of oxygen is a major reason for the resistance of tumor cells to treatments such as
radiotherapies. A large number of recent publications on non-thermal plasma applications in …

Purpose To investigate the clinical implications of a variable relative biological effectiveness
(RBE) on proton dose fractionation. Using acute exposures, the current clinical adoption of a …