Advances in the management of anaplastic thyroid carcinoma: transforming a life-threatening condition into a potentially treatable disease

I Califano, A Smulever, F Jerkovich, F Pitoia - Reviews in Endocrine and …, 2024 - Springer
Anaplastic thyroid cancer (ATC) is an infrequent thyroid tumor that usually occurs in elderly
patients. There is often a history of previous differentiated thyroid cancer suggesting a …

Customizing cancer treatment at the nanoscale: a focus on anaplastic thyroid cancer therapy

J Wang, J Tan, B Wu, R Wu, Y Han, C Wang… - Journal of …, 2023 - Springer
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive kind of thyroid cancer.
Various therapeutic methods have been considered for the treatment of ATC, but its …

Checkpoint Inhibition in Addition to Dabrafenib/Trametinib for BRAFV600E-Mutated Anaplastic Thyroid Carcinoma

S Hamidi, PC Iyer, R Dadu, MK Gule-Monroe… - Thyroid, 2024 - liebertpub.com
Background: The dabrafenib plus trametinib combination (DT) has revolutionized the
treatment of BRAFV600E-mutated anaplastic thyroid carcinoma (BRAFm-ATC). However …

Initial Management of BRAF V600E-Variant Anaplastic Thyroid Cancer: The FAST Multidisciplinary Group Consensus Statement

S Hamidi, R Dadu, ME Zafereo, R Ferrarotto… - JAMA …, 2024 - jamanetwork.com
Importance BRAF/MEK inhibitors revolutionized the treatment ofBRAFV600E-variant
anaplastic thyroid carcinoma (BRAFv-ATC), offering improved outcomes for patients with this …

Strategies for radioiodine treatment: what's new

C Sparano, S Moog, J Hadoux, C Dupuy, A Al Ghuzlan… - Cancers, 2022 - mdpi.com
Simple Summary Radioactive iodine treatment is the oldest targeted therapy for
differentiated thyroid cancer. It can be used for normal thyroid remnant ablation (in order to …

[HTML][HTML] Update on current diagnosis and management of anaplastic thyroid carcinoma

ET Pavlidis, IN Galanis, TE Pavlidis - World Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Well-differentiated thyroid carcinoma has a favorable prognosis with a 5-year survival rate of
over 95%. However, the undifferentiated or anaplastic type accounting for< 0.2%, usually in …

The interplay between vitamin C and thyroid

B Farasati Far, AH Behnoush… - Endocrinology …, 2023 - Wiley Online Library
Introduction Vitamin C (ascorbic acid) is a water‐soluble vitamin, that plays a key role in the
prevention and treatment of scurvy. As vitamin C is an antioxidant and thyroid function may …

Target therapy for BRAF mutated anaplastic thyroid cancer: a clinical and molecular study

TN da Silva, R Rodrigues, A Saramago… - European Journal of …, 2023 - academic.oup.com
Objectives Anaplastic thyroid carcinoma (ATC) has a poor survival. The combination of
Dabrafenib plus Trametinib (DT) had a significant impact in survival of BRAF p. V600E …

Factors associated with survival in anaplastic thyroid carcinoma: A multicenter study from the ENDOCAN-TUTHYREF network

A Jannin, F Giudici, C de la Fouchardière, A Al Ghuzlan… - Thyroid, 2023 - liebertpub.com
Background: Anaplastic thyroid carcinoma (ATC) is a rare and frequently fatal type of thyroid
cancer. The degree of heterogeneity in survival rates for ATC is incompletely studied. This …

Evaluating new treatments for anaplastic thyroid cancer

A Coca-Pelaz, JP Rodrigo, F Lopez… - Expert review of …, 2022 - Taylor & Francis
Introduction Anaplastic thyroid cancer (ATC) is one of the most lethal diseases known to
humans with a median survival of 5 months. The American Thyroid Association (ATA) …