Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Our brains consist of 80% water, which is continuously shifted between different
compartments and cell types during physiological and pathophysiological processes …

Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …

Astrocytes, a subtype of glial cells, come in variety of forms and functions. However,
overarching role of these cell is in the homeostasis of the brain, be that regulation of ions …

The human brain contains two major cell populations, neurons and glia. While neurons are
electrically excitable and capable of discharging short voltage pulses known as action …

Epilepsy is one of the most common chronic neurologic diseases, yet approximately one-
third of affected patients do not respond to anticonvulsive drugs that target neurons or …

Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

Astroglial perisynaptic sheath covers the majority of synapses in the central nervous system.
This glial coverage evolved as a part of the synaptic structure in which elements directly …

Regulation of metabolism is complex and involves enzymes and membrane transporters,
which form networks to support energy dynamics. Lactate, as a metabolic intermediate from …

Astrocytes, which populate the grey and white mater of the brain and the spinal cord are
highly heterogeneous in their morphology and function. These cells are primarily …