Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction
Abstract Dual-specificity phosphatase 6 (DUSP6) serves a specific and conserved function
on the dephosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2). We …
on the dephosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2). We …
LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
Liver regeneration is under metabolic and immune regulation. Despite increasing
recognition of the involvement of neutrophils in regeneration, it is unclear how the liver …
recognition of the involvement of neutrophils in regeneration, it is unclear how the liver …
Neutrophil-specific depletion of gasdermin D does not protect against murine sepsis
The assembly of canonical and noncanonical inflammasomes activates caspase-1 and
caspase-11, respectively, culminating in the cleavage of a common downstream effector …
caspase-11, respectively, culminating in the cleavage of a common downstream effector …
Neutrophil Granulopoiesis Optimized Through Ex Vivo Expansion of Hematopoietic Progenitors in Engineered 3D Gelatin Methacrylate Hydrogels
E Cirves, A Vargas, EE Wheeler… - Advanced …, 2024 - Wiley Online Library
Neutrophils are the first line of defense of the innate immune system. In response to
methicillin‐resistant Staphylococcus aureus infection in the skin, hematopoietic stem, and …
methicillin‐resistant Staphylococcus aureus infection in the skin, hematopoietic stem, and …
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
Acute respiratory distress syndrome (ARDS) is associated with significant morbidity and
mortality, and neutrophils are critical to its pathogenesis. Neutrophil activation is closely …
mortality, and neutrophils are critical to its pathogenesis. Neutrophil activation is closely …
Crystal ribcage: a platform for probing real-time lung function at cellular resolution
Understanding the dynamic pathogenesis and treatment response in pulmonary diseases
requires probing the lung at cellular resolution in real time. Despite advances in intravital …
requires probing the lung at cellular resolution in real time. Despite advances in intravital …
The need for Cre-loci controls in conditional mouse experiments: Mrp8-cre transgene predisposes mice to antibody-induced arthritis
The Cre/loxP system is extensively utilized to pinpoint gene functions in specific cell types or
developmental stages, typically without major disturbance to the host's genome. However …
developmental stages, typically without major disturbance to the host's genome. However …
[PDF][PDF] Probing lung function at high spatiotemporal resolution using a novel crystal ribcage
Real-time, cellular resolution imaging is essential for probing the highly dynamic functions of
the lung at the interface of physics, biology, and immunology. CT and MRI modalities have …
the lung at the interface of physics, biology, and immunology. CT and MRI modalities have …