[HTML][HTML] Natural products in drug discovery: advances and opportunities
AG Atanasov, SB Zotchev, VM Dirsch… - Nature reviews Drug …, 2021 - nature.com
Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
A review of the microbial production of bioactive natural products and biologics
JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …
also known as natural products. Natural products have been a prolific source and an …
Marine natural products
Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235–294 This review covers the
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …
Considerations and caveats in combating ESKAPE pathogens against nosocomial infections
YX Ma, CY Wang, YY Li, J Li, QQ Wan… - Advanced …, 2020 - Wiley Online Library
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …
Retrospective analysis of natural products provides insights for future discovery trends
Understanding of the capacity of the natural world to produce secondary metabolites is
important to a broad range of fields, including drug discovery, ecology, biosynthesis, and …
important to a broad range of fields, including drug discovery, ecology, biosynthesis, and …
Thinking outside the box—novel antibacterials to tackle the resistance crisis
M Lakemeyer, W Zhao, FA Mandl… - Angewandte Chemie …, 2018 - Wiley Online Library
The public view on antibiotics as reliable medicines changed when reports about “resistant
superbugs” appeared in the news. While reasons for this resistance development are easily …
superbugs” appeared in the news. While reasons for this resistance development are easily …
[HTML][HTML] Novel targets to develop new antibacterial agents and novel alternatives to antibacterial agents
TM Belete - Human Microbiome Journal, 2019 - Elsevier
Antibacterial agents have saved many lives and helped the growth of modern medicine over
the past half century. The emergence of drug resistance, jeopardizing the effectiveness of …
the past half century. The emergence of drug resistance, jeopardizing the effectiveness of …
Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals
AS Grillo, AM SantaMaria, MD Kafina, AG Cioffi… - Science, 2017 - science.org
Multiple human diseases ensue from a hereditary or acquired deficiency of iron-transporting
protein function that diminishes transmembrane iron flux in distinct sites and directions …
protein function that diminishes transmembrane iron flux in distinct sites and directions …
Biosynthesis of Tasikamides via Pathway Coupling and Diazonium-Mediated Hydrazone Formation
GL Ma, H Candra, LM Pang, J Xiong… - Journal of the …, 2022 - ACS Publications
Naturally occurring hydrazones are rare despite the ubiquitous usage of synthetic
hydrazones in the preparation of organic compounds and functional materials. In this study …
hydrazones in the preparation of organic compounds and functional materials. In this study …
Exploring an innovative strategy for suppressing bacterial plant disease: excavated novel isopropanolamine-tailored pterostilbene derivatives as potential antibiofilm …
PY Qi, TH Zhang, YM Feng, MW Wang… - Journal of Agricultural …, 2022 - ACS Publications
Bacterial biofilms are the root cause of persistent and chronic phytopathogenic bacterial
infections. Therefore, developing novel agrochemicals that target the biofilm of …
infections. Therefore, developing novel agrochemicals that target the biofilm of …