Nanomaterial-based blood-brain-barrier (BBB) crossing strategies
Increasing attention has been paid to the diseases of central nervous system (CNS). The
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to …
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to …
Design challenges in polymeric scaffolds for tissue engineering
MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …
Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules
MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
Nanomaterial based drug delivery systems for the treatment of neurodegenerative diseases
With an aging population that has been increasing in recent years, the need for the
development of therapeutic approaches for treatment of neurodegenerative disorders (ND) …
development of therapeutic approaches for treatment of neurodegenerative disorders (ND) …
Nanoparticles-mediated emerging approaches for effective treatment of ischemic stroke
W He, Z Zhang, X Sha - Biomaterials, 2021 - Elsevier
Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …
therapeutic substances is a major challenge for effective treatment of ischemic stroke …
Advancements in the use of hydrogels for regenerative medicine: properties and biomedical applications
A Revete, A Aparicio, BA Cisterna… - International Journal …, 2022 - Wiley Online Library
Due to their particular water absorption capacity, hydrogels are the most widely used
scaffolds in biomedical studies to regenerate damaged tissue. Hydrogels can be used in …
scaffolds in biomedical studies to regenerate damaged tissue. Hydrogels can be used in …
Hyaluronic acid biomaterials for central nervous system regenerative medicine
G Jensen, JL Holloway, SE Stabenfeldt - Cells, 2020 - mdpi.com
Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …
Extracellular matrix‐mimetic hydrogels for treating neural tissue injury: a focus on fibrin, hyaluronic acid, and elastin‐like polypeptide hydrogels
DW Nelson, RJ Gilbert - Advanced healthcare materials, 2021 - Wiley Online Library
Neurological and functional recovery is limited following central nervous system injury and
severe injury to the peripheral nervous system. Extracellular matrix (ECM)‐mimetic …
severe injury to the peripheral nervous system. Extracellular matrix (ECM)‐mimetic …
Biomimetic hydrogels with spatial-and temporal-controlled chemical cues for tissue engineering
Biomimetic hydrogels have emerged as the most useful tissue engineering scaffold
materials. Their versatile chemistry can recapitulate multiple physical and chemical features …
materials. Their versatile chemistry can recapitulate multiple physical and chemical features …
3D printed hydrogels with aligned microchannels to guide neural stem cell migration
Following traumatic or ischemic brain injury, rapid cell death and extracellular matrix
degradation lead to the formation of a cavity at the brain lesion site, which is responsible for …
degradation lead to the formation of a cavity at the brain lesion site, which is responsible for …