Molecular genetic advances in uveitis

S Hou, A Kijlstra, P Yang - Progress in molecular biology and translational …, 2015 - Elsevier
Uveitis is usually considered as an intraocular inflammation characterized by variety of
clinical features. Behcet's disease (BD), Vogt–Koyanagi–Harada (VKH) syndrome, acute …

Meta‐analysis of association between cytokine gene polymorphisms and B ehcet's disease risk

Y Liang, WD Xu, M Zhang, LJ Qiu, J Ni… - International Journal …, 2013 - Wiley Online Library
The aim of this study was to perform a meta‐analysis of eligible studies to derive precise
estimation of the association of interleukin‐1 (IL‐1), IL‐10 and tumor necrosis factor (TNF)‐α …

[HTML][HTML] Association of tumor necrosis factor-alpha promoter region gene polymorphism at positions-308G/A,-857C/T, and-863C/A with etanercept response in Iraqi …

S Mohammed, M Zalzala, F Gorial - Archives of Rheumatology, 2022 - ncbi.nlm.nih.gov
Association of tumor necrosis factor-alpha promoter region gene polymorphism at positions -308G/A,
-857C/T, and -863C/A with etanercept response in Iraqi rheumatoid arthritis patients - PMC …

TNFα rs1800629 Polymorphism and Response to Anti-TNFα Treatment in Behçet Syndrome: Data from an Italian Cohort Study

MC Padula, AA Padula, S D'Angelo, N Lascaro… - Journal of Personalized …, 2023 - mdpi.com
Tumor Necrosis Factor-alpha (TNFα) rs1800629 (-308G> A) is a single nucleotide
polymorphism (SNP) related to variable responses to anti-TNFα therapy. This therapy is …

[PDF][PDF] A single nucleotide polymorphism in the FOXP3 gene associated with Behcet's disease in an Iranian population

D Shanehbandi, S Gholizadeh, A Khabazi, E Sakhinia - Clin. Lab, 2015 - genetictabriz.com
Background: Behçet's Disease (BD) is a rare autoimmune disease that involves the
dysfunction of regulatory T cells. FOXP3 is a key transcription factor in the development and …

[HTML][HTML] Polymorphisms in the tumor necrosis factor gene and susceptibility to Behcet's disease: an updated meta-analysis

M Zhang, WD Xu, PF Wen, Y Liang, J Liu, HF Pan… - Molecular …, 2013 - ncbi.nlm.nih.gov
Methods A systematic literature search was conducted to identify all relevant studies. Pooled
odds ratios (ORs) with 95% confidence intervals (CIs) were used to estimate the strength of …

Genetic association between TNFA polymorphisms (Rs1799964 and Rs361525) and susceptibility to cancer in systemic sclerosis

J Kosałka-Węgiel, S Lichołai, S Dziedzina, M Milewski… - Life, 2022 - mdpi.com
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine that plays an important role in
the pathogenesis of autoimmune diseases. The aim of the study was to establish an …

UVEOGENE: an SNP database for investigations on genetic factors associated with uveitis and their relationship with other systemic autoimmune diseases

Q Wang, G Su, X Tan, J Deng, L Du, X Huang… - Human …, 2019 - Wiley Online Library
Uveitis is an intraocular inflammatory disease which can lead to serious visual impairment.
Genetic factors have been shown to be involved in its development. However, few …

Association of polymorphisms in TNF and GRN genes with ankylosing spondylitis in a Chinese Han population

N Hu, Y Cui, Q Yang, L Wang, X Yang, H Xu - Rheumatology International, 2018 - Springer
The aim of this study is to investigate the association of the polymorphisms in tumor necrosis
factor (TNF) and granulin (GRN) with ankylosing spondylitis (AS) in a Chinese Han …

Association Analysis of IL10, TNF-α, and IL23R-IL12RB2 SNPs with Behçet's Disease Risk in Western Algeria

O Khaib Dit Naib, M Aribi, A Idder, A Chiali… - Frontiers in …, 2013 - frontiersin.org
Objective: We have conducted the first study of the association of interleukin (IL)-10, tumor
necrosis factor alpha (TNF-α), and IL23R-IL12RB2 region single nucleotide polymorphisms …