Glucocorticoids (GCs) are an important component of adaptive response of an organism to
stressogenic stimuli, a typical stress response being accompanied by elevation of GC levels …

Seizure disorders are common, affecting both the young and the old. Currently available
antiseizure drugs are ineffective in a third of patients and have been developed with a focus …

Background Temporal lobe epilepsy (TLE) is the most common form of partial epilepsy and
is accompanied, in one third of cases, by resistance to antiepileptic drugs (AED). Most AED …

Epilepsy is one of the serious neurological sequelae of bacterial meningitis. Rifampicin, the
well-known broad spectrum antibiotic, is clinically used for chemoprophylaxis of meningitis …

Anti-inflammatory therapies are the current most plausible drug candidates for anti-
epileptogenesis and neuroprotection following prolonged seizures. Given that vasogenic …

Cerebrolysin (CBL), a mixture of several active peptide fragments and neurotrophic factors
including brain-derived neurotrophic factor (BDNF), is currently used in the management of …

The objective of this study was to evaluate the effect of dexamethasone, on the severity of
seizures and levels of pro-inflammatory interleukins in animals with kindling model induced …

Abstract Objective Infection with Theiler's murine encephalomyelitis virus (TMEV) in
C57Bl/6J mice results in handling‐induced seizures and is useful for evaluating compounds …

The status epilepticus (SE) induced by lithium-pilocarpine is a well characterized rodent
model of the human temporal lobe epilepsy (TLE) which is accompanied by severe brain …

Inflammation is one of the mechanisms involved in seizure induction. In this study, the effect
of minocycline, an anti-inflammatory drug, was investigated on kindling acquisition …