Single-cell immunology of SARS-CoV-2 infection
Gaining a better understanding of the immune cell subsets and molecular factors associated
with protective or pathological immunity against severe acute respiratory syndrome …
with protective or pathological immunity against severe acute respiratory syndrome …
Computational flow cytometry: helping to make sense of high-dimensional immunology data
Recent advances in flow cytometry allow scientists to measure an increasing number of
parameters per cell, generating huge and high-dimensional datasets. To analyse, visualize …
parameters per cell, generating huge and high-dimensional datasets. To analyse, visualize …
OMIP‐069: forty‐color full spectrum flow cytometry panel for deep immunophenotyping of major cell subsets in human peripheral blood
LM Park, J Lannigan, MC Jaimes - Cytometry Part A, 2020 - Wiley Online Library
PURPOSE AND APPROPRIATE SAMPLE TYPES This 40‐color flow cytometry‐based panel
was developed for in‐depth immunophenotyping of the major cell subsets present in human …
was developed for in‐depth immunophenotyping of the major cell subsets present in human …
Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial
M Alberer, U Gnad-Vogt, HS Hong, KT Mehr, L Backert… - The Lancet, 2017 - thelancet.com
Background Vaccines based on mRNA coding for antigens have been shown to be safe and
immunogenic in preclinical models. We aimed to report results of the first-in-human proof-of …
immunogenic in preclinical models. We aimed to report results of the first-in-human proof-of …
CyTOF workflow: differential discovery in high-throughput high-dimensional cytometry datasets
High-dimensional mass and flow cytometry (HDCyto) experiments have become a method
of choice for high-throughput interrogation and characterization of cell populations. Here, we …
of choice for high-throughput interrogation and characterization of cell populations. Here, we …
IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure
Abstract Exposure to Mycobacterium tuberculosis (Mtb) results in heterogeneous clinical
outcomes including primary progressive tuberculosis and latent Mtb infection (LTBI). Mtb …
outcomes including primary progressive tuberculosis and latent Mtb infection (LTBI). Mtb …
Current approaches to HIV vaccine development: a narrative review
Introduction The development of an effective vaccine to protect against HIV is a longstanding
global health need complicated by challenges inherent to HIV biology and to the execution …
global health need complicated by challenges inherent to HIV biology and to the execution …
Persistent cellular immunity to SARS-CoV-2 infection
SARS-CoV-2 is responsible for an ongoing pandemic that has affected millions of
individuals around the globe. To gain further understanding of the immune response in …
individuals around the globe. To gain further understanding of the immune response in …
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
T Kammann, C Cai, T Sekine, E Mouchtaridi… - Science …, 2024 - science.org
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize
microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 …
microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 …
Cytomegalovirus-specific T-cell reconstitution following letermovir prophylaxis after hematopoietic cell transplantation
D Zamora, ER Duke, H Xie, BC Edmison… - Blood, The Journal …, 2021 - ashpublications.org
Decreased cytomegalovirus (CMV)-specific immunity after hematopoietic cell transplantation
(HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir …
(HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir …