DNA helicases unwind or rearrange duplex DNA during replication, recombination and
repair. Helicases of many pathogenic organisms such as viruses, bacteria, and protozoa …

Accurate and integral cellular DNA replication is modulated by multiple replication‐
associated proteins, which is fundamental to preserve genome stability. Furthermore …

Exploring the molecular difference among breast cancer subtypes is of crucial importance in
understanding its heterogeneity and seeking its effective clinical treatment. For this, several …

Initiation of eukaryotic DNA synthesis occurs at origins of replication that are utilized with
characteristic times and frequencies during S phase. We have investigated origin usage by …

Background The infective schistosome cercaria develops within the intramolluscan daughter
sporocyst from an undifferentiated germ ball, during which synthesis of proteins essential for …

Cdc45 is an essential protein that together with Mcm2-7 and GINS forms the eukaryotic
replicative helicase CMG. Cdc45 seems to be rate limiting for the initial unwinding or firing of …

Little is known about mammalian preRC stoichiometry, the number of preRCs on
chromosomes, and how this relates to replicon size and usage. We show here that, on …

Purpose Hub genes are good molecular candidates for targeted cancer therapy. As yet,
however, there is little information on the clinical implications and functional characteristics …

The Hippo pathway regulates cell proliferation and apoptosis through the Yes-associated
protein (YAP) transcriptional activator. YAP has a well-described role in promoting cell …

Cervical cancer is the fourth most common malignancy in women worldwide and cervical
squamous cell carcinoma (CESC) is the most common histological type of cervical cancer …