Epigenetics of aging and aging-associated diseases
D Saul, RL Kosinsky - International journal of molecular sciences, 2021 - mdpi.com
Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …
Over the past decades, several hallmarks of aging have been defined, including epigenetic …
Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease
M Tsalenchuk, SM Gentleman, SJ Marzi - npj Parkinson's Disease, 2023 - nature.com
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …
complex risk structure thought to be influenced by interactions between genetic variants and …
Epigenetic mechanisms of aging and aging-associated diseases
A la Torre, F Lo Vecchio, A Greco - Cells, 2023 - mdpi.com
Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …
Epigenetic regulation of neuroinflammation in Parkinson's disease
Neuroinflammation is one of the most significant factors involved in the initiation and
progression of Parkinson's disease. PD is a neurodegenerative disorder with a motor …
progression of Parkinson's disease. PD is a neurodegenerative disorder with a motor …
Implications of diet and the gut microbiome in neuroinflammatory and neurodegenerative diseases
S Hirschberg, B Gisevius, A Duscha… - International journal of …, 2019 - mdpi.com
Within the last century, human lifestyle and dietary behaviors have changed dramatically.
These changes, especially concerning hygiene, have led to a marked decrease in some …
These changes, especially concerning hygiene, have led to a marked decrease in some …
Microtubule acetylation dyshomeostasis in Parkinson's disease
P Naren, KS Samim, KP Tryphena, LK Vora… - Translational …, 2023 - Springer
The inter-neuronal communication occurring in extensively branched neuronal cells is
achieved primarily through the microtubule (MT)-mediated axonal transport system. This …
achieved primarily through the microtubule (MT)-mediated axonal transport system. This …
Epigenetic basis of lead-induced neurological disorders
T Wang, J Zhang, Y Xu - … journal of environmental research and public …, 2020 - mdpi.com
Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …
Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain
L Toker, GT Tran, J Sundaresan, OB Tysnes… - Molecular …, 2021 - Springer
Background Parkinson's disease (PD) is a complex, age-related neurodegenerative
disorder of largely unknown etiology. PD is strongly associated with mitochondrial …
disorder of largely unknown etiology. PD is strongly associated with mitochondrial …
The role of DNA methylation and histone modifications in neurodegenerative diseases: a systematic review
Importance Epigenetic modifications of the genome, such as DNA methylation and histone
modifications, have been reported to play a role in neurodegenerative diseases (ND) such …
modifications, have been reported to play a role in neurodegenerative diseases (ND) such …
The role of epigenetic changes in preeclampsia
A Kamrani, I Alipourfard, H Ahmadi‐Khiavi… - Biofactors, 2019 - Wiley Online Library
Preeclampsia (PE) is a disorder affecting 2–10% of pregnancies and has a major role for
perinatal and maternal mortality and morbidity. PE can be occurred by initiation of new …
perinatal and maternal mortality and morbidity. PE can be occurred by initiation of new …