A rising number of researchers are interested in thiophene-based analogs as they have
wide possibilities of biological potential in the largely developing chemical world of the …

In medicinal chemistry, 2-aminothiophene is a central five-membered heterocyclic core that
is mostly synthesized using Gewald methodology. Its incorporation into a molecule can …

Abstract The hydrolysis of substituted 3-(3-cyanothiophen-2-yl) imino-3 H-furan-2-ones was
studied. It was found that the reaction proceeds with the opening of the furan ring and the …

Abstract New spiro [cyclohexane-1, 2'-thiazolo [4, 5-b] pyridine derivatives (3–23) were
investigated. Then there is in vitro antimicrobial potency against possible organisms …

Abstract Spiro [benzo [h] quinoline-7, 3′-indoline] diones and spiro [indoline-3, 4′-
pyrazolo [3, 4-b] quinoline] diones were efficiently synthesized via one-pot multi-component …

Abstract New thieno [2, 3-b] pyridine clubbed various thiazole ring systems were
synthesized by the reaction of 2-(1-(3-amino-4, 6-dimethylthieno [2, 3-b] pyridin-2-yl) …

The synthesis of eight novel pyrazole-tetrazole compounds are presented. Their structures
are identified by NMR and FTIR spectroscopy, mass spectrometry as well as elemental …

An efficient protocol for the synthesis of thiophene derivatives from β-ketothioamides (KTAs)
and vinyl azides via [3+ 2] cycloaddition process catalyzed by InCl 3 was developed. This …

A series of new thiophene derivatives was prepared through nucleophilic substitution
reactions of the precursor N-(4-substituted-phenyl)-5-(2-chloroacetamido)-4-cyano-3 …

The alkylation of 4-hydroxythiocoumarins (1a–f) was carried out with various allyl bromides
as well as propargyl bromides using K2CO3 (2 equiv.) in anhydrous acetone at room …