The potent actions of pigment epithelium-derived factor (PEDF) on tumour-associated cells,
and its extracellular localization and secretion, stimulated research on this multifunctional …

The main cause of cancer-related mortality, metastasis, is a complex, multi-step process.
The extracellular matrix (ECM) component of solid tumors has been implicated in metastatic …

Osteogenesis imperfecta (OI) is a heterogeneous genetic disorder characterized by bone
fragility and susceptibility to fractures after minimal trauma. After mutations in all known OI …

Adult stem cells are characterized by self-renewal and multilineage differentiation, and these
properties seem to be regulated by signals from adjacent differentiated cell types and by …

Purpose To determine the molecular basis of corneal avascularity during wound healing
and determine the role of angiogenic and antiangiogenic factors in corneal vasculogenesis …

Pigment epithelium-derived factor (PEDF) is a potent and broadly acting neurotrophic factor
that protects neurons in many regions of the central nervous system against insults such as …

Idiopathic pulmonary fibrosis (IPF) is a disabling disease of the lung parenchyma,
characterized by progressive accumulation of scar tissue and myofibroblast activation after …

Pigment epithelium-derived factor (PEDF) is an extracellular multifunctional protein
belonging to the serpin superfamily with demonstrable neurotrophic, gliastatic …

Corneal avascularity is necessary for the preservation of optimal vision. The cornea
maintains a dynamic balance between pro-and antiangiogenic factors that allows it to …

Pigment epithelium-derived factor (PEDF) is a broadly expressed multifunctional member of
the serine proteinase inhibitor (serpin) family. This widely studied protein plays critical roles …