Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Over the last two decades, nanoparticulate delivery systems have revolutionized cancer
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …

Chemotherapy is often used to treat retinoblastoma; however, this treatment method has
severe systemic adverse effects and inadequate therapeutic effectiveness. Extracellular …

Malignant neoplasms are one of the main causes of death, especially in children, on a
global scale, despite strenuous efforts made at advancing both diagnostic and therapeutic …

Treatment of retinoblastoma is limited due to its delayed detection and inaccesbility of drugs
to reach the retina crossing the blood-retinal barrier. With the advancements in …

Gene silencing through RNA interference (RNAi), particularly using small double-stranded
RNA (siRNA), has been identified as a potent strategy for targeted cancer treatment. Yet, its …

Retinoblastoma (RB) and uveal melanoma (UM) are the most common primary intraocular
tumors in children and adults, respectively. Despite continued increases in the likelihood of …

Improving surgical resection outcomes for locally aggressive tumors is key to inducing
durable locoregional disease control and preventing progression to metastatic disease …

Background Retinoblastoma (RB) is a rare type of pediatric ocular cancer with difficulty in
treatment and detection owing to alterations in tumor suppressor genes and the lack of …

The development of biomaterials for protein delivery is an emerging field that spans
materials science, bioengineering, and medicine. In this review, we highlight the immense …