Y-box-binding protein 1 (YB-1) and its functions
IA Eliseeva, ER Kim, SG Guryanov… - Biochemistry …, 2011 - Springer
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
Cold shock proteins: from cellular mechanisms to pathophysiology and disease
JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …
presence of one or more cold shock domains. In humans, the best characterized members of …
LncRNA HIF1A-AS1 promotes gemcitabine resistance of pancreatic cancer by enhancing glycolysis through modulating the AKT/YB1/HIF1α pathway
F Xu, M Huang, Q Chen, Y Niu, Y Hu, P Hu, D Chen… - Cancer research, 2021 - AACR
Gemcitabine (GEM) resistance is a major challenge for chemotherapy of pancreatic cancer.
Previous studies have reported on the role of long noncoding RNA (lncRNA) in …
Previous studies have reported on the role of long noncoding RNA (lncRNA) in …
Integrin-linked kinase–essential roles in physiology and cancer biology
PC McDonald, AB Fielding… - Journal of cell …, 2008 - journals.biologists.com
Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions
and regulates many cellular processes, including growth, proliferation, survival …
and regulates many cellular processes, including growth, proliferation, survival …
A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
YB-1: oncoprotein, prognostic marker and therapeutic target?
Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …
changes required for the development and persistence of tumours [Hanahan and Weinberg …
YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer
D Jiang, T Qiu, J Peng, S Li, Tala, W Ren… - Cell Death & …, 2022 - nature.com
Y-box binding protein 1 (YB-1) is a well-known oncogene highly expressed in various
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …
Role of focal adhesion kinase in regulating YB–1–mediated paclitaxel resistance in ovarian cancer
Y Kang, W Hu, C Ivan, HJ Dalton… - Journal of the …, 2013 - academic.oup.com
Background We previously found focal adhesion kinase (FAK) inhibition sensitizes ovarian
cancer to taxanes; however, the mechanisms are not well understood. Methods We …
cancer to taxanes; however, the mechanisms are not well understood. Methods We …
Predicting patient response with models trained on cell lines and patient-derived xenografts by nonlinear transfer learning
Preclinical models have been the workhorse of cancer research, producing massive
amounts of drug response data. Unfortunately, translating response biomarkers derived from …
amounts of drug response data. Unfortunately, translating response biomarkers derived from …
YB-1 as an oncoprotein: functions, regulation, post-translational modifications, and targeted therapy
Q Yin, M Zheng, Q Luo, D Jiang, H Zhang, C Chen - Cells, 2022 - mdpi.com
Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …