Primary and secondary immune thrombocytopenia (ITP): Time for a rethink

TJ González-López, D Provan, A Bárez… - Blood Reviews, 2023 - Elsevier
There are not many publications that provide a holistic view of the management of primary
and secondary ITP as a whole, reflecting the similarities and differences between the two …

Pediatric refractory immune thrombocytopenia: A systematic review

L Ibrahim, SX Dong, K O'Hearn… - Pediatric Blood & …, 2023 - Wiley Online Library
Pediatric immune thrombocytopenia (ITP) is an acquired disorder associated with
autoimmune destruction and impairment of platelet production in children. Some children …

The role of CD8+ T-cell clones in immune thrombocytopenia

A Malik, AA Sayed, P Han, MMH Tan… - Blood, The Journal …, 2023 - ashpublications.org
Immune thrombocytopenia (ITP) is traditionally considered an antibody-mediated disease.
However, a number of features suggest alternative mechanisms of platelet destruction. In …

Platelet enhancement by Carica papaya L. leaf fractions in cyclophosphamide induced thrombocytopenic rats is due to elevated expression of CD110 receptor on …

C Nandini, SRV Madhunapantula, VR Bovilla… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Carica papaya leaf juice/decoction has been in use in folk
medicine in Srilanka, Malaysia and in few parts of India for enhancing the platelet counts in …

A proposal for new definition (s) and management approach to paediatric refractory ITP: Reflections from the Intercontinental ITP Study Group

C Neunert, KMJ Heitink‐Polle… - British Journal of …, 2023 - Wiley Online Library
Immune thrombocytopenia (ITP) in children is a relatively mild and self‐limited disorder with
the majority of children demonstrating normalization of platelet count by 12 months from …

Rilzabrutinib versus placebo in adults and adolescents with persistent or chronic immune thrombocytopenia: LUNA 3 phase III study

DJ Kuter, JB Bussel, W Ghanima… - Therapeutic …, 2023 - journals.sagepub.com
Background: Immune thrombocytopenia (ITP) is characterized by primarily autoantibody-
mediated platelet destruction and impaired platelet production resulting in thrombocytopenia …

[HTML][HTML] Idiopathic thrombocytopenic purpura: current limitations and management

R Thakre, P Gharde, M Raghuwanshi - Cureus, 2023 - ncbi.nlm.nih.gov
Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, is a
blood disorder characterized by a reduction in the number of platelets. A reduction in the …

Psychometric evaluation of ITP life quality index (ILQI) in a global survey of patients with immune thrombocytopenia

R Viana, D D'Alessio, L Grant, N Cooper, D Arnold… - Advances in …, 2021 - Springer
Introduction Immune thrombocytopenia (ITP) is an autoimmune disorder caused by
immunologic destruction of otherwise normal platelets. Patients and physicians differ in their …

Treatment outcomes and adherence to treatment in patients with immune thrombocytopenia in two Ethiopian teaching hospitals: a retrospective cohort study

DA Beyene, EA Sisay, AM Fentie, A Gebremedhin - Scientific Reports, 2024 - nature.com
The treatment of immune thrombocytopenia (ITP) is challenging and treatment outcomes
depend on numerous unknown and patient-specific factors. Corticosteroids are the …

Scoping review on epigenetic mechanisms in primary immune thrombocytopenia

JH Tan, AHS Ahmad Azahari, A Ali, NAS Ismail - Genes, 2023 - mdpi.com
Immune Thrombocytopenia (ITP) is an autoimmune blood disorder that involves multiple
pathways responsible for the homeostasis of the immune system. Numerous pieces of …