Reelin through the years: From brain development to inflammation
Reelin was originally identified as a regulator of neuronal migration and synaptic function,
but its non-neuronal functions have received far less attention. Reelin participates in organ …
but its non-neuronal functions have received far less attention. Reelin participates in organ …
Reelin: neurodevelopmental architect and homeostatic regulator of excitatory synapses
CR Wasser, J Herz - Journal of Biological Chemistry, 2017 - ASBMB
Over half a century ago, DS Falconer first reported a mouse with a reeling gate. Four
decades later, the Reln gene was isolated and identified as the cause of the reeler …
decades later, the Reln gene was isolated and identified as the cause of the reeler …
Cardiac and intestinal tissue conduct developmental and reparative processes in response to lymphangiocrine signaling
Lymphatic vessels conduct a diverse range of activities to sustain the integrity of surrounding
tissue. Besides facilitating the movement of lymph and its associated factors, lymphatic …
tissue. Besides facilitating the movement of lymph and its associated factors, lymphatic …
Galectin-3 deletion reduces LPS and acute colitis-induced pro-inflammatory microglial activation in the ventral mesencephalon
AM Espinosa-Oliva, P García-Miranda… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease is a highly prevalent neurological disorder for which there is currently
no cure. Therefore, the knowledge of risk factors as well as the development of new putative …
no cure. Therefore, the knowledge of risk factors as well as the development of new putative …
Decreased generation of C‐terminal fragments of ApoER2 and increased reelin expression in Alzheimer's disease
T Mata‐Balaguer, I Cuchillo‐Ibañez… - The FASEB …, 2018 - Wiley Online Library
Increasing evidence indicates that altered reelin signaling could contribute to synaptic
dysfunction in Alzheimer's disease (AD). We found that reelin protein and mRNA levels were …
dysfunction in Alzheimer's disease (AD). We found that reelin protein and mRNA levels were …
Identification of RELN variant p.(Ser2486Gly) in an Iranian family with ankylosing spondylitis; the first association of RELN and AS
Ankylosing spondylitis (AS) is a common complex inflammatory disease; however, up to now
distinct genes with monogenic pattern have not been reported for this disease. In the present …
distinct genes with monogenic pattern have not been reported for this disease. In the present …
Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases
L Calvier, A Alexander, AT Marckx, MZ Kounnas… - Cells, 2024 - mdpi.com
Reelin, a large extracellular glycoprotein, plays critical roles in neuronal development and
synaptic plasticity in the central nervous system (CNS). Recent studies have revealed non …
synaptic plasticity in the central nervous system (CNS). Recent studies have revealed non …
[HTML][HTML] Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes
AE Carvajal, JM Serrano-Morales… - … et Biophysica Acta (BBA …, 2017 - Elsevier
We previously reported that reelin, an extracellular matrix protein first known for its key role
in neuronal migration, reduces the susceptibility to dextran sulphate sodium (DSS)-colitis …
in neuronal migration, reduces the susceptibility to dextran sulphate sodium (DSS)-colitis …
The Inflammation-Induced Dysregulation of Reelin Homeostasis Hypothesis of Alzheimer's Disease
BS Reive, V Lau, CL Sánchez-Lafuente… - Journal of …, 2024 - content.iospress.com
Alzheimer's disease (AD) accounts for most dementia cases, but we lack a complete
understanding of the mechanisms responsible for the core pathology associated with the …
understanding of the mechanisms responsible for the core pathology associated with the …
Reelin Protects against Colon Pathology via p53 and May Be a Biomarker for Colon Cancer Progression
JM Serrano-Morales, MD Vázquez-Carretero… - Biology, 2022 - mdpi.com
Simple Summary Colon cancer is a multifactorial disease involving genetic, environmental
and lifestyle risk factors. Despite being one of the most common malignancies and a leading …
and lifestyle risk factors. Despite being one of the most common malignancies and a leading …