Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that
involve G-quartets linked by loop nucleotides. The structural and topological diversity of G …

Guanine (G)-quadruplexes (G4s) are unique nucleic acid structures that are formed by
stacked G-tetrads in G-rich DNA or RNA sequences. G4s have been reported to play …

G-quadruplex DNA has been viewed as a prospective anti-cancer target owing to its
potential biological relevance. Real-time monitoring of DNA G-quadruplex structures in …

Because of the absence of methods for tracking RNA G‐quadruplex dynamics, especially
the folding and unfolding of this attractive structure in live cells, understanding of the …

G-quadruplexes are four-stranded nucleic acid secondary structures that are formed in
guanine-rich sequences. G-quadruplexes are widely distributed in functional regions of the …

Genome integrity is essential for proper cell function such that genetic instability can result in
cellular dysfunction and disease. Mutations in the human genome are not random, and …

The detection and stabilization of G-quadruplexes (G4s) in living systems is of enormous
applicability in the fields of chemical biology and therapeutic materials. Whereas DNA …

Mitochondria is the cell's energy powerhouse and regulate most of the metabolism process
through the inherent mitochondrial genes (mtDNA). The control of mtDNA replication and …

A novel thiazole orange based fluorescent probe NCT has been reported with promising G-
quadruplex targeting ability. Interacting with G-quadruplexes will enhance its fluorescence …

G-quadruplex has attracted considerable attention due to their prevalent distribution in
functional genomic regions and transcripts, which can importantly influence biological …