The current review and synthesis was designed to provocatively develop and evaluate the
proposition that “fear of the unknown may be a, or possibly the, fundamental fear”(Carleton …

The longitudinal stability of personality is low in childhood but increases substantially into
adulthood. Theoretical explanations for this trend differ in the emphasis placed on intrinsic …

Objective: The transmission of anxiety within families is well recognized, but the underlying
processes are poorly understood. Twin studies of adolescent anxiety demonstrate both …

Learning to respond to others' distress with well-regulated empathy is an important
developmental task linked to positive health outcomes and moral achievements. However …

Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …

Understanding the nature and influence of specific risk profiles is increasingly important for
health behavior promotion. The purpose of this article is to document the value of two factors …

Emotional and behavioural problems in childhood and adolescence can be chronic and are
predictive of future psychiatric problems. Understanding what factors drive the development …

Background Mindfulness‐based therapies have been shown to be effective in treating
depression and reducing cognitive biases. Anxiety sensitivity is one cognitive bias that may …

Anxiety sensitivity and distress tolerance are both hypothesized risk factors for generalized
anxiety disorder (GAD) and major depressive disorder (MDD). However, it is unclear …

Background Despite being considered a measure of environmental risk, reported life events
are partly heritable. One mechanism that may contribute to this heritability is genetic …