Peroxisome proliferator‐activated receptor‐γ coactivator (PGC)‐1α is a transcriptional
coactivator described as a master regulator of mitochondrial biogenesis and function …

The role of mitochondrial function in health and disease has become increasingly
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …

Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide.
Oxidative stress and inflammation are pathophysiological processes involved in the …

Cardiovascular disease (CVD) is the leading cause of disease-related death worldwide and
a significant obstacle to improving patients' health and lives. Mitochondria are core …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Metformin is the oldest and most commonly used first-line antidiabetic drug because of its
good clinical efficacy, high safety, low cost and easy access. At the same time, in recent …

Cardiovascular disease (CVD) remains the most common cause of death worldwide and
has become a public health concern. The proven notable risk factors for CVD are …

Mitochondria, the membrane-bound cell organelles that supply most of the energy needed
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …

Microplastics (MPs) are new persistent organic pollutants derived from the degradation of
plastics. They can accumulate along the food chain and enter the human body through oral …

Acute myocardial infarction is the leading cause of cardiovascular‑related mortality and
chronic heart failure worldwide. As regards treatment, the reperfusion of ischemic tissue …