Normal alpha-fetoprotein hepatocellular carcinoma: are they really normal?

CW Lee, HI Tsai, WC Lee, SW Huang, CY Lin… - Journal of clinical …, 2019 - mdpi.com
Introduction: serum alpha-fetoprotein (AFP) was routinely employed as a tumor marker for
screening, diagnosis, and treatment follow-up of hepatocellular carcinoma (HCC). However …

Current discovery strategies for hepatocellular carcinoma therapeutics

Q Dai, C Zhang, Z Yuan, Q Sun… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: The global incidence of hepatocellular carcinoma (HCC) is not expected to
decline significantly over the next 30 years. And although the latest gene sequencing …

[HTML][HTML] Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients

A Alzamzamy, H Elsayed, M Abd Elraouf… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Hepatocellular carcinoma (HCC) accounts for 8.2% of all cancer-related
deaths worldwide. Being a vascular tumor, vascular endothelial growth factor (VEGF) plays …

The role of circulating soluble fms-like tyrosine kinase-1 in patients with diabetic foot ulcer: A possible mechanism of pathogenesis via a novel link between oxidative …

SR Abd El-Khalik, YM Hafez, RA Elkholy - Microvascular Research, 2020 - Elsevier
Background Diabetic foot ulcer (DFU) is one of the most devastating diabetic consequences
leading to amputations. Oxidative stress, inflammation, vascular insufficiency and …

Growth factor-induced angiogenesis in hepatocellular carcinoma

S Muppala - Critical Reviews™ in Oncogenesis, 2021 - dl.begellhouse.com
Hepatocellular carcinoma (HCC), which accounts for~ 90% of total liver cancer cases, is
considered to be the second leading cause of death globally. Tumor vasculature has been …

Polymorphisms of base-excision repair genes and the hepatocarcinogenesis

MAM Mattar, ARN Zekri, N Hussein, H Morsy, G Esmat… - Gene, 2018 - Elsevier
Aim To determine the possible association between polymorphisms of DNA repair genes,
including XRCC1 Arg194Tryp, Arg280His, and Arg399Glu, APE1 Asp148Glu, and NEIL2 …

Detection of exosomal miR-18a and miR-222 levels in Egyptian patients with hepatic cirrhosis and hepatocellular carcinoma

EA Elghoroury, EE Abdelghaffar… - International …, 2022 - journals.sagepub.com
Background Hepatocellular carcinoma (HCC) is known to be the second leading cause of
cancer-related mortality worldwide. For improving the prognosis as well as reducing the rate …

Cinnamaldehyde relieves induced hepatocellular carcinoma in rat model via targeting wnt/β-catenin pathway

ASG Abd El Salam, YA Samra… - Scientia Pharmaceutica, 2022 - mdpi.com
Cinnamaldehyde (CA) is a natural compound that has promising biological activity. The
current study investigates the antitumor activity of CA in thioacetamide induced …

P18 peptide, a functional fragment of pigment epithelial-derived factor, inhibits angiogenesis in hepatocellular carcinoma via modulating VEGF/VEGFR2 signalling …

X Wang, P Xiu, F Wang, J Zhong, H Wei… - Oncology …, 2017 - spandidos-publications.com
The P18 peptide is a functional fragment of pigment epithelial-derived factor (PEDF), which
is an endogenic angiogenesis inhibitor. This study sought to determine the anti-angiogenic …

[HTML][HTML] Glypican-3, vascular endothelial growth factor and golgi protein-73 for differentiation between liver cirrhosis and hepatocellular carcinoma

S Mamdouh, A Soliman, F Khorshed… - Asian Pacific Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Hepatocellular carcinoma (HCC) accounts for more than 80% of primary liver
cancers. Moreover, in the next 10 years, more than one million patients are expected to die …