[HTML][HTML] A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: Where exposomics meets metabolomics

J Sun, R Fang, H Wang, DX Xu, J Yang, X Huang… - Environment …, 2022 - Elsevier
Humans are exposed to an ever-increasing number of environmental toxicants, some of
which have gradually been elucidated to be important risk factors for metabolic diseases …

Advances and applications of machine learning and deep learning in environmental ecology and health

S Cui, Y Gao, Y Huang, L Shen, Q Zhao, Y Pan… - Environmental …, 2023 - Elsevier
Abstract Machine learning (ML) and deep learning (DL) possess excellent advantages in
data analysis (eg, feature extraction, clustering, classification, regression, image recognition …

Liquid crystal monomer: a potential PPARγ antagonist

H Zhao, C Li, MY Naik, J Wu, A Cardilla… - Environmental …, 2023 - ACS Publications
Liquid crystal monomers (LCMs) are a large family of artificial ingredients that have been
widely used in global liquid crystal display (LCD) industries. As a major constituent in LCDs …

[HTML][HTML] Probabilistic risk assessment–the keystone for the future of toxicology

A Maertens, E Golden, TH Luechtefeld, S Hoffmann… - Altex, 2022 - ncbi.nlm.nih.gov
Safety sciences must cope with uncertainty of models and results as well as information
gaps. Acknowledging this uncertainty necessitates embracing probabilities and accepting …

Integration of target, suspect, and nontarget screening with risk modeling for per-and polyfluoroalkyl substances prioritization in surface waters

J Hu, Y Lyu, H Chen, L Cai, J Li, X Cao, W Sun - Water Research, 2023 - Elsevier
Though thousands of per-and polyfluoroalkyl substances (PFAS) have been on the global
market, most research focused on only a small fraction, potentially resulting in …

Application of ToxCast/Tox21 data for toxicity mechanism-based evaluation and prioritization of environmental chemicals: Perspective and limitations

J Jeong, D Kim, J Choi - Toxicology in Vitro, 2022 - Elsevier
In response to the need to minimize the use of experimental animals, new approach
methodologies (NAMs) using advanced technology have emerged in the 21st century …

Exposome in human health: utopia or wonderland?

M Fang, L Hu, D Chen, Y Guo, J Liu, C Lan, J Gong… - The Innovation, 2021 - cell.com
The current human exposome primarily emphasizes the total environmental exposure
during an entire life. The characteristics of" lifelong" and" all environmental factors" make it …

HExpPredict: In Vivo Exposure Prediction of Human Blood Exposome Using a Random Forest Model and Its Application in Chemical Risk Prioritization

F Zhao, L Li, P Lin, Y Chen, S Xing, H Du… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Due to many substances in the human exposome, there is a dearth of
exposure and toxicity information available to assess potential health risks. Quantification of …

[HTML][HTML] National temporal trend for organophosphate pesticide DDT exposure and associations with chronic kidney disease using age-adapted eGFR model

J Lv, L Guo, Y Gu, Y Xu, Q Xue, X Yang… - Environment …, 2022 - Elsevier
Whilst certain environmental organochlorine pesticide exposure may still pose significant
burden, the associations between dichloro-diphenyl-trichloroethane (DDT) and chronic …

Non-target discovery and risk prediction of per-and polyfluoroalkyl substances (PFAS) and transformation products in wastewater treatment systems

T Liu, LX Hu, Y Han, S Xiao, LL Dong, YY Yang… - Journal of Hazardous …, 2024 - Elsevier
Wastewater treatment plants (WWTPs) serve as the main destination of many wastes
containing per-and polyfluoroalkyl substances (PFAS). Here, we investigated the occurrence …