Origins of modern human ancestry
New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …
origins of modern human ancestry. Here we review our current understanding of how the …
[HTML][HTML] Did our species evolve in subdivided populations across Africa, and why does it matter?
We challenge the view that our species, Homo sapiens, evolved within a single population
and/or region of Africa. The chronology and physical diversity of Pleistocene human fossils …
and/or region of Africa. The chronology and physical diversity of Pleistocene human fossils …
The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes
S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …
While the raw data for the vast majority are fully publicly available testifying to the …
Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition
Population size history is essential for studying human evolution. However, ancient
population size history during the Pleistocene is notoriously difficult to unravel. In this study …
population size history during the Pleistocene is notoriously difficult to unravel. In this study …
Age of the oldest known Homo sapiens from eastern Africa
Efforts to date the oldest modern human fossils in eastern Africa, from Omo-Kibish,–and
Herto, in Ethiopia, have drawn on a variety of chronometric evidence, including 40Ar/39Ar …
Herto, in Ethiopia, have drawn on a variety of chronometric evidence, including 40Ar/39Ar …
Pliocene and Eocene provide best analogs for near-future climates
KD Burke, JW Williams, MA Chandler… - Proceedings of the …, 2018 - National Acad Sciences
As the world warms due to rising greenhouse gas concentrations, the Earth system moves
toward climate states without societal precedent, challenging adaptation. Past Earth system …
toward climate states without societal precedent, challenging adaptation. Past Earth system …
Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation
We conduct high coverage (> 30×) whole-genome sequencing of 180 individuals from 12
indigenous African populations. We identify millions of unreported variants, many predicted …
indigenous African populations. We identify millions of unreported variants, many predicted …
Ancient DNA and deep population structure in sub-Saharan African foragers
Multiple lines of genetic and archaeological evidence suggest that there were major
demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of …
demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of …
Imputation of ancient human genomes
Due to postmortem DNA degradation and microbial colonization, most ancient genomes
have low depth of coverage, hindering genotype calling. Genotype imputation can improve …
have low depth of coverage, hindering genotype calling. Genotype imputation can improve …
African genetic diversity and adaptation inform a precision medicine agenda
The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …
humans more than 300,000 years ago, has resulted in high genetic diversity and …