Origins of modern human ancestry

A Bergström, C Stringer, M Hajdinjak, EML Scerri… - Nature, 2021 - nature.com
New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

[HTML][HTML] Did our species evolve in subdivided populations across Africa, and why does it matter?

EML Scerri, MG Thomas, A Manica, P Gunz… - Trends in ecology & …, 2018 - cell.com
We challenge the view that our species, Homo sapiens, evolved within a single population
and/or region of Africa. The chronology and physical diversity of Pleistocene human fossils …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition

W Hu, Z Hao, P Du, F Di Vincenzo, G Manzi, J Cui… - Science, 2023 - science.org
Population size history is essential for studying human evolution. However, ancient
population size history during the Pleistocene is notoriously difficult to unravel. In this study …

Age of the oldest known Homo sapiens from eastern Africa

CM Vidal, CS Lane, A Asrat, DN Barfod, DF Mark… - Nature, 2022 - nature.com
Efforts to date the oldest modern human fossils in eastern Africa, from Omo-Kibish,–and
Herto, in Ethiopia, have drawn on a variety of chronometric evidence, including 40Ar/39Ar …

Pliocene and Eocene provide best analogs for near-future climates

KD Burke, JW Williams, MA Chandler… - Proceedings of the …, 2018 - National Acad Sciences
As the world warms due to rising greenhouse gas concentrations, the Earth system moves
toward climate states without societal precedent, challenging adaptation. Past Earth system …

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

S Fan, JP Spence, Y Feng, MEB Hansen, J Terhorst… - Cell, 2023 - cell.com
We conduct high coverage (> 30×) whole-genome sequencing of 180 individuals from 12
indigenous African populations. We identify millions of unreported variants, many predicted …

Ancient DNA and deep population structure in sub-Saharan African foragers

M Lipson, EA Sawchuk, JC Thompson, J Oppenheimer… - Nature, 2022 - nature.com
Multiple lines of genetic and archaeological evidence suggest that there were major
demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of …

Imputation of ancient human genomes

B Sousa da Mota, S Rubinacci, DI Cruz Dávalos… - Nature …, 2023 - nature.com
Due to postmortem DNA degradation and microbial colonization, most ancient genomes
have low depth of coverage, hindering genotype calling. Genotype imputation can improve …

African genetic diversity and adaptation inform a precision medicine agenda

L Pereira, L Mutesa, P Tindana, M Ramsay - Nature Reviews Genetics, 2021 - nature.com
The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …