Developmental hematopoiesis consists of multiple, partially overlapping hematopoietic
waves that generate the differentiated blood cells required for embryonic development while …

Regenerative medicine harnesses the body's innate capacity for self-repair to restore
malfunctioning tissues and organs. Stem cell therapies represent a key regenerative …

Cellular mechanisms whereby quiescent stem cells sense tissue injury and transition to an
activated state are largely unknown. Quiescent skeletal muscle stem cells (MuSCs, also …

Mammalian stem cells govern development, tissue homeostasis, and regeneration.
Following years of study, their functions have been delineated with increasing precision. The …

Although it is well described that mitochondria are at the epicentre of the energy demands of
a cell, it is becoming important to consider how each cell tailors its mitochondrial …

Introduction Human dental pulp stem cells (hDPSCs) reside in specialized
microenvironments in the dental pulp, termed “niches,” which are composed of diverse …

Multiple processes control quiescence of muscle stem cells (MuSCs), which is instrumental
to guarantee long-term replenishment of the stem cell pool. Here, we describe that the G …

Septins are considered the fourth component of the cytoskeleton with the septin7 isoform
playing a critical role in the formation of diffusion barriers in phospholipid bilayers and intra …

Multiple sclerosis (MS) is a chronic inflammatory, autoimmune, and neurodegenerative
disease of the central nervous system (CNS), characterized by demyelination and axonal …

Adipose-derived stem cells (ADSCs) are promising in regenerative medicine. Their
proliferation, survival and activation are influenced by specific signals within their …