Micro-CT acquisition and image processing to track and characterize pulmonary nodules in mice

M Zaw Thin, C Moore, T Snoeks, T Kalber… - Nature …, 2023 - nature.com
X-ray computed tomography is a reliable technique for the detection and longitudinal
monitoring of pulmonary nodules. In preclinical stages of diagnostic or therapeutic …

Advances in preclinical PET

SS Adler, J Seidel, PL Choyke - Seminars in nuclear medicine, 2022 - Elsevier
The classical intent of PET imaging is to obtain the most accurate estimate of the amount of
positron-emitting radiotracer in the smallest possible volume element located anywhere in …

Characterization of a preclinical PET insert in a 7 tesla MRI scanner: beyond NEMA testing

W Gsell, C Molinos, C Correcher… - Physics in Medicine …, 2020 - iopscience.iop.org
This study evaluates the performance of the Bruker positron emission tomograph (PET)
insert combined with a BioSpec 70/30 USR magnetic resonance imaging (MRI) scanner …

Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators

M Dadgar, S Parzych, J Baran, N Chug, C Curceanu… - Ejnmmi physics, 2023 - Springer
Background Alongside the benefits of Total-Body imaging modalities, such as higher
sensitivity, single-bed position, low dose imaging, etc., their final construction cost prevents …

Spatial multiplexing and omics

JL Carstens, SN Krishnan, A Rao, AG Sorace… - Nature Reviews …, 2024 - nature.com
Much like solving a game of Clue, understanding physiological mysteries involves
answering who, what, when and where. Multiomics approaches delve into cellular and …

PbI2–TiO2 Bulk Heterojunctions with Long-Range Ordering for X-ray Detectors

Q Wen, W Ma, Y Liu, X Jin, J Ren, C Lin… - The Journal of …, 2021 - ACS Publications
High-performance X-ray detectors are usually based on single crystals, due to the long-
range ordering and hence outstanding electronic properties. On the other hand, bulk …

Deep learning framework to synthesize high-count preclinical PET images from low-count preclinical PET images

K Dutta, Z Liu, R Laforest, A Jha… - Medical Imaging 2022 …, 2022 - spiedigitallibrary.org
Preclinical PET imaging is widely used to quantify in vivo biological and metabolic process
at molecular level in small animal imaging. In preclinical PET, low-count acquisition has …

A deep neural network to recover missing data in small animal pet imaging: comparison between sinogram-and image-domain implementations

M Amirrashedi, S Sarkar, H Ghadiri… - 2021 IEEE 18th …, 2021 - ieeexplore.ieee.org
Missing areas in PET sinograms and severe image artifacts as a consequence thereof, still
gain prominence not only in sparse-ring detector configurations but also in full-ring PET …

Dose reduction and image enhancement in micro‐CT using deep learning

FM Muller, J Maebe, C Vanhove… - Medical …, 2023 - Wiley Online Library
Background In preclinical settings, micro‐computed tomography (CT) provides a powerful
tool to acquire high resolution anatomical images of rodents and offers the advantage to in …

Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source

J Peñas, A Alejo, A Bembibre, JI Apiñaniz… - Scientific Reports, 2024 - nature.com
Most advanced medical imaging techniques, such as positron-emission tomography (PET),
require tracers that are produced in conventional particle accelerators. This paper focuses …