The first report demonstrating the therapeutic efficacy of an orally applied neurokinin-1
(NK1) receptor antagonist in depression was published 10 years ago. Although there were …

Epidemiological studies have begun to suggest obesity is a risk factor for chronic migraine,
although no causal relationship has been established, and risk factors for progression from …

BACKGROUND: Major depressive disorder (MDD) is inconsistently associated with
elevations in proinflammatory cytokines and neuropeptides. We used a skin sweat patch …

Mouse models show that experimental stress mimicking prolonged life-stress exposure
enhances neurogenic inflammation, induces adaptive immunity cytokine-imbalance …

Purpose To assess relative quality of life in patients with strabismus. Design Retrospective
cohort study. Methods The 25-item National Eye Institute Visual Functioning Questionnaire …

Major depressive disorder (MDD) is one of the most common psychiatric illnesses in the
adult population. It is often associated with an increased risk of cardiovascular disease …

Prior studies evaluating predictors of pain-related outcomes following treatment for sciatica
have been limited by methodological problems, including retrospective study design, use of …

Maternal environmental factors have been demonstrated to exert significant influences on
the health of offspring. The hypothalamic-pituitary-adrenal (HPA) axis is an important …

This study was carried out to assess the prevalence of major depressive disorder (MDD) in
persons suffering from pain symptoms in various locations, both with and without comorbid …

Purpose Major depressive disorder (MDD) has detrimental effects on health-related quality
of life (HRQoL). We describe the effect of vortioxetine on HRQoL in MDD patients by using …