OBJECTIVES: Irritable bowel syndrome (IBS) is a chronic functional bowel disorder that is
thought to be due to a disorder of brain–gut function. Drugs acting centrally, such as …

Interoception refers to the process by which the nervous system senses and integrates
signals originating from within the body, providing a momentary mapping of the body's …

Irritable bowel syndrome (IBS) is a highly prevalent, chronic disorder that significantly
reduces patients' quality of life. Advances in diagnostic testing and in therapeutic options for …

Irritable bowel syndrome (IBS) is the most prevalent of the functional gastrointestinal
disorders (FGIDs). Current estimates are that IBS affects up to 10–12% of adults in North …

We provide a general framework for understanding functional gastrointestinal disorders
(FGIDs) from a biopsychosocial perspective. More specifically, we provide an overview of …

Irritable bowel syndrome (IBS) is a common, symptom-based condition that has negative
effects on quality of life and costs health care systems billions of dollars each year. Until …

METHODS We have conducted a series of systematic reviews on the efficacy of therapy in
IBS and CIC. There have been several systematic reviews of therapy for IBS and CIC …

Objectives National guidelines for the management of irritable bowel syndrome (IBS)
recommend that psychological therapies should be considered, but their relative efficacy is …

The broad role of stress in the brain-gut axis is widely acknowledged, with implications for
multiple prevalent health conditions that are characterized by chronic gastrointestinal …

OBJECTIVES: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal
disorder. Evidence relating to the treatment of this condition with antidepressants and …