Inflammation, and the pain that accompanies it, is a natural response of the body. The
licorice plant (Glycyrrhiza glabra) have demonstrated anti-inflammatory, anti-edematous …

In the 1990s, the identification of a non-selective ion channel, especially responsive to
capsaicin, revolutionized the studies of somatosensation and pain that were to follow. The …

Transient receptor potential vanilloid 1 (TRPV1) has been implicated in peripheral
inflammation and is a mediator of the inflammatory response to various noxious stimuli …

Background Remote ischemic preconditioning (RIPC) refers to a brief episode of exposure
to potential adverse stimulation and prevents injury during subsequent exposure. RIPC has …

Background Aryl-propionic acid derivatives with ibuprofen as representative drug are very
important for therapy, being recommended especially for anti-inflammatory and analgesic …

Ethnopharmacological relevance The leaves of Eugenia species are widely used in popular
medicine to treat several diseases, such as arthritis, rheumatism and diabetes. Eugenia …

Background Magnesium is an antagonist of the N-methyl-D-aspartate receptor. This study
aimed to investigate the anti-edematous effect of magnesium sulfate (MS) in different …

The aim of this study was to evaluate the functional interaction of Glycyrrhiza glabra root
extract (GGRE) on the large conductance Ca2+-activated K+ (BKCa) channels expressed in …

Background and Aims: The object of this study was the investigation of the central
antinociceptive effects of naringin as well as the association of stimulation of opioidergic …

Piper nigrum is one of the most familiar spices due to its' pharmacological and physiological
properties. Piperine is a main active alkaloid of Piper nigrum with a broad spectrum of …